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. 2022 Sep 1;5(9):e2233446.
doi: 10.1001/jamanetworkopen.2022.33446.

Evaluation of Risk Factors for Postbooster Omicron COVID-19 Deaths in England

Vahé Nafilyan  1 , Isobel L Ward  1 , Chris Robertson  2   3 , Aziz Sheikh  4 ; National Core Studies—Immunology Breakthrough Consortium
Affiliations

Evaluation of Risk Factors for Postbooster Omicron COVID-19 Deaths in England

Vahé Nafilyan et al. JAMA Netw Open. .

Erratum in

  • Error in Table.
    [No authors listed] [No authors listed] JAMA Netw Open. 2022 Sep 1;5(9):e2238101. doi: 10.1001/jamanetworkopen.2022.38101. JAMA Netw Open. 2022. PMID: 36173638 Free PMC article. No abstract available.

Abstract

This cohort study of adults in England evaluates the association of sociodemographic and clinical risk factors with death from COVID-19 among individuals who completed primary vaccination and received a messenger RNA (mRNA) booster.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Roberston reported service as a member of UK and Scottish government advisory committees, including the Scientific Pandemic Influenza Group on Modeling, Scottish Government Scientific Advisory Committee, and Medicines and Healthcare products Regulatory Agency COVID vaccine benefit and risk expert working group. Dr Sheikh reported service in uncompensated advisory roles on COVID-19 to UK and Scottish Governments and AstraZeneca. No other disclosures were reported.

Figures

Figure.
Figure.. Risk Factors for Death From COVID-19 After Receiving a Booster
Hazard ratios (HRs) were calculated with a Cox regression model. In panel A, the reference for HRs are men with healthy body mass index (BMI, which is calculated as weight in kilograms divided by height in meters squared) in index of multiple deprivation (IMD) quintile 1 for 50 days since last booster. In panels B and C, the dashed lines illustrate an HR of 1. Prior fracture includes fractures of the hip, wrist, spine, or humerus. COPD indicates chronic obstructive pulmonary disease; SCID, severe combined immunodeficiency; SLE, systemic lupus erythematosus; TIA, transient ischemic attack.
See this image and copyright information in PMC

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