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Review
. 2022 Jan-Mar;63(1):203-207.
doi: 10.47162/RJME.63.1.22.

Fetal sacrococcygeal immature teratoma - report of two cases and review of the literature

Mădălina Lucia Marcu  1 , Nicolae Bacalbaşa, Elisabeta Candrea, Cătălina Diana Stănică, Tarig Massawi, Andreea Chirilov, Adrian Neacşu, Irina Pacu
Affiliations
Review

Fetal sacrococcygeal immature teratoma - report of two cases and review of the literature

Mădălina Lucia Marcu et al. Rom J Morphol Embryol. 2022 Jan-Mar.

Abstract

Sacrococcygeal teratomas (SCTs) are rare congenital tumors. With the improvement of diagnostic imaging methods and follow-up protocols in pregnancies, in utero detection of these tumors has increased. Despite these progresses, SCTs may present difficulties in establishing in utero diagnosis and subsequent management. We present two cases of SCT in 18 weeks, respectively 22 weeks pregnancy, diagnosed using ultrasound imaging and pathologically confirmed. Also, the article aims to recapitulate clinicopathological aspects and prognosis of these lesions, following the review of the literature.

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Conflict of interest statement

The authors declare that they have no conflict of interests.

Figures

Figure 1
Figure 1
Macroscopic appearance of the fetal sacrococcygeal tumor (A). On cross-section (B), the tumor showed mixed (solid and cystic) structure
Figure 2
Figure 2
The lesion includes glandular structures and rosettes of nervous tissue (A), as well as cartilaginous foci (B). Hematoxylin–Eosin (HE) staining: (A and B) ×100
Figure 3
Figure 3
General macroscopic image of Case No. 2 (A) with a sacrococcygeal tumor of nodular, well defined, predominantly solid aspect on cross-section (B)
Figure 4
Figure 4
Microscopic examination shows mature and immature nervous tissue arranged in rosettes and neuroepithelial tubes (A), squamous epithelium and glandular structures (B), and cartilaginous foci (C). HE staining: (A–C) ×50
See this image and copyright information in PMC

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