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Case Reports
. 1987 May;14(2):156-8.
doi: 10.1017/s0317167100026305.

Treatment of paramyotonia congenita with acetazolamide

T J Benstead, P R Camfield, D B King
Case Reports

Treatment of paramyotonia congenita with acetazolamide

T J Benstead et al. Can J Neurol Sci. 1987 May.

Abstract

Treatment of paramyotonia congenita with acetazolamide has been shown to reduce myotonic symptoms but severe weakness has developed in some patients leading to a recommendation not to use the drug in this disorder. We studied a patient with the characteristic clinical and electrophysiological profile of paramyotonia congenita. Myotonia was effectively treated with a very low dose of acetazolamide and no weakness developed. We conclude that acetazolamide can be a safe and effective medication in paramyotonia congenita.

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