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Case Reports
. 1987 Sep;28(1):137-44.
doi: 10.1016/0165-4608(87)90363-3.

Clonal chromosome abnormalities in two liposarcomas

F Mertens, B Johansson, N Mandahl, S Heim, K Bennet, A Rydholm, H Willén, F Mitelman
Case Reports

Clonal chromosome abnormalities in two liposarcomas

F Mertens et al. Cancer Genet Cytogenet. 1987 Sep.

Abstract

Two liposarcomas were analyzed with chromosome banding technique. The sole chromosomal abnormality in one of the tumors, a mixed type (myxoid and round cell) liposarcoma, was t(12;16)(q13;p11), a rearrangement previously reported to be associated with myxoid liposarcoma. The other tumor, a pleomorphic liposarcoma, displayed massive numerical rearrangements (modal chromosome number 94-112), and numerous, mostly unidentifiable, marker chromosomes. The following clonal structural aberrations were recognized: del(1)(p22), del(1)(q23), t(7;?)(p22;?), i(17q), and t(19;?)(q13;?).

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