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. 2022 Aug 28;11(17):5050.
doi: 10.3390/jcm11175050.

Radiation Exposure among Patients with Inflammatory Bowel Disease: A Single-Medical-Center Retrospective Analysis in Taiwan

Chen-Ta Yang  1   2 , Hsu-Heng Yen  1   2   3   4 , Yang-Yuan Chen  1   5 , Pei-Yuan Su  1   2 , Siou-Ping Huang  1
Affiliations

Radiation Exposure among Patients with Inflammatory Bowel Disease: A Single-Medical-Center Retrospective Analysis in Taiwan

Chen-Ta Yang et al. J Clin Med. .

Abstract

Inflammatory bowel disease (IBD) is a chronic and relapsing disease that can be complicated by abscesses, fistulas, or strictures of the damaged bowel. Endoscopy or imaging studies are required to diagnose and monitor the treatment response or complications of the disease. Due to the low incidence of the disease in Taiwan, the pattern of radiation exposure from medical imaging has not been well studied previously. This retrospective study aimed to evaluate the pattern of radiation exposure in 134 Taiwanese IBD patients (45 CD and 89 UC) diagnosed and followed at Changhua Christian Hospital from January 2010 to December 2020. We reviewed the patient demographic data and radiation-containing image studies performed during the follow-up. The cumulative effective dose (CED) was calculated for each patient. During a median follow-up of 4 years, the median CED was higher for patients with CD (median CED 21.2, IQR 12.1−32.8) compared to patients with UC (median CED 2.1, IQR 0−5.6) (p < 0.001). In addition, the CD patients had a trend of a higher rate of cumulative ≥50 mSv compared with the UC patients (6.7% vs. 1.1%, p = 0.110). In conclusion, our study found a higher radiation exposure among CD patients compared to patients with UC, representing the complicated nature of the disease. Therefore, increasing the use of radiation-free medical imaging such as intestinal ultrasound or magnetic resonance imaging should be advocated in daily practice to decrease the risk of excessive radiation exposure in these patients.

Keywords: Crohn’s disease; imaging; inflammatory bowel disease; radiation.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Flow chart of patient enrollment in the present study.
Figure 2
Figure 2
Kaplan–Meier analysis showing a significant difference in the cumulative probability of exposure to CED ≥ 50 mSv after diagnosis between different IBD types, surgery, or hospital admission status.
Figure 2
Figure 2
Kaplan–Meier analysis showing a significant difference in the cumulative probability of exposure to CED ≥ 50 mSv after diagnosis between different IBD types, surgery, or hospital admission status.
See this image and copyright information in PMC

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