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Editorial
. 2022 Sep 3;11(17):5216.
doi: 10.3390/jcm11175216.

How Did We End Up Using a Quadruple Guided Therapy Combining At Least Two Antibiotics with a PPI to Eradicate Helicobacter pylori?

Maxime Pichon  1   2 , Julie Cremniter  1   2 , Christophe Burucoa  1   2
Affiliations
Editorial

How Did We End Up Using a Quadruple Guided Therapy Combining At Least Two Antibiotics with a PPI to Eradicate Helicobacter pylori?

Maxime Pichon et al. J Clin Med. .

Abstract

Since the discovery of Helicobacter pylori, and even if the species is frequently susceptible to many antibiotics in vitro, only six of them (amoxicillin, clarithromycin, metronidazole, tetracycline, levofloxacin, and rifabutin) and bismuth salts could be considered as effective in vivo to eliminate H pylori and have been used in recommended eradication treatments [...].

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Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Malfertheiner P., Megraud F., O’Morain C.A., Gisbert J.P., Kuipers E.J., Axon A.T., Bazzoli F., Gasbarrini A., Atherton J., Graham D.Y., et al. Management of Helicobacter Pylori Infection-the Maastricht V/Florence Consensus Report. Gut. 2017;66:6–30. doi: 10.1136/gutjnl-2016-312288. - DOI - PubMed
    1. McNulty C.A., Gearty J.C., Crump B., Davis M., Donovan I.A., Melikian V., Lister D.M., Wise R. Campylobacter Pyloridis and Associated Gastritis: Investigator Blind, Placebo Controlled Trial of Bismuth Salicylate and Erythromycin Ethylsuccinate. Br. Med. J. 1986;293:645–649. doi: 10.1136/bmj.293.6548.645. - DOI - PMC - PubMed
    1. Logan R.P., Gummett P.A., Hegarty B.T., Walker M.M., Baron J.H., Misiewicz J.J. Clarithromycin and Omeprazole for Helicobacter Pylori. Lancet. 1992;340:239. doi: 10.1016/0140-6736(92)90502-T. - DOI - PubMed
    1. Sakurai Y., Mori Y., Okamoto H., Nishimura A., Komura E., Araki T., Shiramoto M. Acid-Inhibitory Effects of Vonoprazan 20 Mg Compared with Esomeprazole 20 Mg or Rabeprazole 10 Mg in Healthy Adult Male Subjects—A Randomised Open-Label Cross-over Study. Aliment. Pharmacol. Ther. 2015;42:719–730. doi: 10.1111/apt.13325. - DOI - PubMed
    1. Lamouliatte H., Cayla R., Zerbib F., Forestier S., de Mascarel A., Joubert-Collin M., Mégraud F. Dual Therapy Using a Double Dose of Lansoprazole with Amoxicillin versus Triple Therapy Using a Double Dose of Lansoprazole, Amoxicillin, and Clarithromycin to Eradicate Helicobacter Pylori Infection: Results of a Prospective Randomized Open Study. Am. J. Gastroenterol. 1998;93:1531–1534. doi: 10.1111/j.1572-0241.1998.00280.x. - DOI - PubMed

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