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. 1987;33(4):240-2.
doi: 10.1159/000238501.

Penetration of norfloxacin into human prostatic tissue following single-dose oral administration

M Dan, J Golomb, A Gorea, A Lindner, S A Berger

Penetration of norfloxacin into human prostatic tissue following single-dose oral administration

M Dan et al. Chemotherapy. 1987.

Abstract

Concomitant concentrations of norfloxacin in serum, urine and prostatic tissue were determined in 12 patients following a single oral dose of 400 mg. Tissue levels ranged from 0.3 to 1.73 mg/kg, and therapeutic concentrations were demonstrable for as long as 8 h following dosage. The mean ratio of tissue to serum concentration was 1.01 +/- (SE) 0.13.

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