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. 1987;33(4):255-8.
doi: 10.1159/000238504.

In vitro susceptibility of Mycobacterium avium to a new macrolide (RU-28965)

M Casal, F Rodriguez, R Villalba

In vitro susceptibility of Mycobacterium avium to a new macrolide (RU-28965)

M Casal et al. Chemotherapy. 1987.

Abstract

The in vitro susceptibility of Mycobacterium avium to RU-28965 alone and in combination with rifampin, isoniazid, and sulfametoxipiridazine was studied by the agar dilution method. The synergistic effect of the RU-28965 with rifampin has been demonstrated. At a concentration of 16 micrograms/ml or lower of RU-28965, 100% of M. avium strains were inhibited. If 2 micrograms/ml of rifampin is added the MIC of RU-28965 is lowered to 0.25 microgram/ml.

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