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. 2022 Oct;41(10):1348-1356.
doi: 10.1016/j.healun.2022.07.020. Epub 2022 Jul 30.

The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Twenty-fifth pediatric lung transplantation report - 2022; focus on pulmonary vascular diseases

Don Hayes Jr  1 , Wida S Cherikh  1 , Michael O Harhay  1 , Michael Perch  1 , Eileen Hsich  1 , Luciano Potena  1 , Aparna Sadavarte  1 , Anne Zehner  1 , Tajinder P Singh  1 , Andreas Zuckermann  1 , Josef Stehlik  2 ; International Society for Heart and Lung Transplantation  1
Affiliations

The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Twenty-fifth pediatric lung transplantation report - 2022; focus on pulmonary vascular diseases

Don Hayes Jr et al. J Heart Lung Transplant. 2022 Oct.
No abstract available

Keywords: children; heart-lung; lung; pulmonary hypertension; pulmonary vascular disease; transplant.

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Conflict of interest statement

Disclosure statement Michael Perch received an institutional research grant from Roche, Ambu, Zambon, consultant fees from Takeda, Zambon, PulmonX, Mallinkrodt, GSK, Novartis, Boeringer-Ingelheim. Michael O. Harhay received consulting fees from Trinity life sciences. Luciano Potena received consulting fees from Biotest, Novartis, Takeda, Sandoz and CareDx. Andreas Zuckermann served on the speakers bureau of Paragonix, Mallinckrodt, Medtronik and Franz Kohler Chemie, and received research grants from Biotest and Xvivo. Josef Stehlik received consulting fees for Medtronic, Natera, Sanofi-Aventis, Transmedics and research support from Natera; Wida S. Cherikh, Aparna Sadavarte, Kelsi Lindblad and Anne Zehner received funding from ISHLT; Don Hayes, Jr., Eileen Hsich and Tajinder P. Singh do not have any relevant financial disclosures.

Figures

Figure 1
Figure 1
Diagnosis distribution by location and era (transplants: January 1992-June 2018).
Figure 2
Figure 2
Median recipient (A) age (PVD transplant: January 1992-June 2018), (B) body mass index (transplant: January 1992-June 2018), by year.
Figure 3
Figure 3
Cumulative incidence of retransplant (primary PVD transplants: January 1995-June 2017).
Figure 4
Figure 4
Kaplan-Meier survival within 12 months by era (PVD transplants: January 2000-June 2017).
Figure 5
Figure 5
Kaplan-Meier survival within 12 months by recipient age (PVD transplants: January 2000-June 2017).
Figure 6
Figure 6
Kaplan-Meier survival within 12 months by diagnosis (transplants: January 2000-June 2017).
Figure 7
Figure 7
Kaplan-Meier survival within 12 months by diagnosis (transplants: January 2000-June 2017).
Figure 8
Figure 8
Kaplan-Meier Survival within 12 months by recipient estimated GFR (PVD transplants: January 2000-June 2017). GFR was estimated using the modified Schwartz formula.
Figure 9
Figure 9
Kaplan-Meier survival within 12 months by procedure type (PVD transplants: January 2000-June 2017).
Figure 10
Figure 10
Kaplan-Meier survival within 5 years conditional on survival to 1 year by era (PVD transplants: January 1996-June 2013).
Figure 11
Figure 11
Kaplan-Meier survival within 5 years conditional on survival to 1 year by recipient age (PVD transplants: January 1996-June 2013).
Figure 12
Figure 12
Kaplan-Meier survival within 5 years conditional on survival to 1 year by diagnosis (transplants: January 1996-June 2013).
Figure 13
Figure 13
Kaplan-Meier survival within 5 years conditional on survival to 1 year by diagnosis (transplants: January 1996-June 2013).
Figure 14
Figure 14
Kaplan-Meier survival within 5 years conditional on survival to 1 year by recipient estimated GFR (PVD transplants: January 1996-June 2013). GFR was estimated using the modified Schwartz formula.
Figure 15
Figure 15
Kaplan-Meier survival within 5 years conditional on survival to 1 year by procedure type (PVD transplants: January 1996-June 2013).
Figure 16
Figure 16
Kaplan-Meier freedom from bronchiolitis obliterans syndrome/chronic lung allograft dysfunction (BOS/CLAD) conditional on survival to discharge by era (PVD transplants: January 1996-June 2013).
Figure 17
Figure 17
Kaplan-Meier freedom from bronchiolitis obliterans syndrome/chronic lung allograft dysfunction (BOS/CLAD) conditional on survival to discharge by recipient age (PVD transplants: January 1996-June 2013).
Figure 18
Figure 18
Statistically significant categorical risk factors for 5-year mortality conditional on survival to 1 year with 95% confidence limits (PVD transplants: January 1987-June 2013, N = 411).
See this image and copyright information in PMC

References

    1. Hayes D Jr, Cherikh WS, Chambers DC, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: twenty-second pediatric lung and heart-lung transplantation report-2019; focus theme: donor and recipient size match. J Heart Lung Transplant 2019;38:1015–27. - PMC - PubMed
    1. Chambers DC, Cherikh WS, Harhay MO, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: thirty-sixth adult lung and heart-lung transplantation report-2019; focus theme: donor and recipient size match. J Heart Lung Transplant 2019;38:1042–55. - PMC - PubMed
    1. Rossano JW, Singh TP, Cherikh WS, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: twenty-second pediatric heart transplantation report - 2019; focus theme: donor and recipient size match. J Heart Lung Transplant 2019;38:1028–41. - PMC - PubMed
    1. Khush KK, Cherikh WS, Chambers DC, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: thirty-sixth adult heart transplantation report - 2019; focus theme: donor and recipient size match. J Heart Lung Transplant 2019;38:1056–66. - PMC - PubMed
    1. Hayes D Jr, Harhay MO, Cherikh WS, et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: twenty-third pediatric lung transplantation report - 2020; focus on deceased donor characteristics. J Heart Lung Transplant 2020;39:1038–49. - PMC - PubMed