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. 2022 Oct-Dec;40(4):582-584.
doi: 10.1016/j.ijmmb.2022.08.010. Epub 2022 Sep 8.

Pulmonary nocardiosis: Risk factors and species distribution from a high burden centre

Marilyn M Ninan  1 , Manigandan Venkatesan  2 , V Balaji  2 , Priscilla Rupali  3 , Joy S Michael  2
Affiliations

Pulmonary nocardiosis: Risk factors and species distribution from a high burden centre

Marilyn M Ninan et al. Indian J Med Microbiol. 2022 Oct-Dec.

Abstract

Nocardiosis is a clinical and diagnostic challenge. This was a retrospective study carried out on cases of pulmonary nocardiosis presenting over 15 years. Clinical data was retrieved using the electronic patient records. Vitek MS 3.2 (MALDI TOF MS) was carried out on 22 isolates and sequencing on another 9 isolates. Of 71 patients presenting with pulmonary nocardiosis, 58 (81.6%) were on immunosuppressant therapy, 26 (46%) had a previous lung pathology, 11 (8%) were HIV associated. Disseminated disease was seen in 6 (8.4%). There were 8 (11.26%) deaths in this cohort of patients. Of 31/71 identified to species, the most common were Nocardia cyriacigeorgica (n ​= ​11) followed by Nocardia farcinica (n ​= ​9).

Keywords: MALDI TOF; Nocardiosis; Pulmonary; Sequencing.

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Conflict of interest statement

Declaration of competing interest The authors have no conflicts to disclose.

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