Sustained drug-related reaction with eosinophilia and systemic symptoms (DRESS) triggered by low molecular weight heparins in COVID-19: management and precision diagnosis

Affiliations

¹ Department of Medical and Surgical Sciences, Chair of Allergology and Clinical Immunology, University of Foggia, Foggia, Italy.
² Department of Medical and Surgical Sciences, Chair of Respiratory Diseases, University of Foggia, Foggia, Italy.
³ Department of Emergency and Organ Transplantation, School and Chair of Allergology and Clinical Immunology, University of Bari - Aldo Moro, Bari, Italy.

Elena Minenna et al. Postepy Dermatol Alergol. 2022 Aug.

. 2022 Aug;39(4):816-818.

doi: 10.5114/ada.2021.109586. Epub 2021 Oct 1.

¹ Department of Medical and Surgical Sciences, Chair of Allergology and Clinical Immunology, University of Foggia, Foggia, Italy.
² Department of Medical and Surgical Sciences, Chair of Respiratory Diseases, University of Foggia, Foggia, Italy.
³ Department of Emergency and Organ Transplantation, School and Chair of Allergology and Clinical Immunology, University of Bari - Aldo Moro, Bari, Italy.

No abstract available

Conflict of interest statement

The authors declare no conflict of interest.

Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS): Focus on the Pathophysiological and Diagnostic Role of Viruses.
Ramirez GA, Ripa M, Burastero S, Benanti G, Bagnasco D, Nannipieri S, Monardo R, Ponta G, Asperti C, Cilona MB, Castagna A, Dagna L, Yacoub MR. Ramirez GA, et al. Microorganisms. 2023 Jan 30;11(2):346. doi: 10.3390/microorganisms11020346. Microorganisms. 2023. PMID: 36838310 Free PMC article. Review.
Novel approach to idursulfase and laronidase desensitization in type 2 and type 1 S mucopolysaccharidosis (MPS).
Spataro F, Viggiani F, Macchia DG, Rollo V, Tummolo A, Suppressa P, Sabba' C, Rossi MP, Giliberti L, Satriano F, Nettis E, Di Bona D, Caiaffa MF, Fischetto R, Macchia L. Spataro F, et al. Orphanet J Rare Dis. 2022 Nov 3;17(1):402. doi: 10.1186/s13023-022-02556-7. Orphanet J Rare Dis. 2022. PMID: 36329518 Free PMC article.

1. Tang N, Bai H, Chen X, et al. . Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy. J Thromb Haemost 2020; 18: 1094-9. - PMC - PubMed
1. Harr T, Scherer K, Tsakiris DA, Bircher AJ. Immediate type hypersensitivity to low molecular weight heparins and tolerance of unfractionated heparin and fondaparinux. Allergy 2006; 61: 787-8. - PubMed
1. Cesana P, Scherer K, Bircher AJ. Immediate type hypersensitivity to heparins: two case reports and a review of the literature. Int Arch Allergy Immunol 2016; 171: 285-9. - PubMed
1. Ronceray S, Dinulescu M, Le Gall F, et al. . Enoxaparin-induced DRESS syndrome. Case Rep Dermatol 2012; 4: 233-7. - PMC - PubMed
1. Porebski G, Gschwend-Zawodniak A, Pichler WJ. In vitro diagnosis of T-cell mediated drug allergy. Clin Exp Allergy 2011; 41: 461-70. - PubMed