doi: 10.1016/0014-2999(87)90191-9.
Intracerebroventricular neuropeptide Y protects against stress-induced gastric erosion in the rat
- PMID: 3609132
- DOI: 10.1016/0014-2999(87)90191-9
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Intracerebroventricular neuropeptide Y protects against stress-induced gastric erosion in the rat
Eur J Pharmacol.
.
Abstract
The effects of intracerebroventricular administration of neuropeptide Y (NPY) on stress-induced gastric erosion in the rat were investigated. Animals were exposed to water immersion stress after a single injection of 2 nmol NPY. Stress-induced erosion was reduced by approximately 50%. The plasma corticosterone levels were not affected. We interpret the protective effect of NPY as a manifestation of its sedative properties.
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