Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Mar-Apr;67(2):205.
doi: 10.4103/ijd.ijd_754_21.

Genital Psoriasis: A Prospective, Observational, Single-Centre Study on Prevalence, Clinical Features, Risk Factors, and Its Impact on Quality of Life and Sexual Health

Affiliations

Genital Psoriasis: A Prospective, Observational, Single-Centre Study on Prevalence, Clinical Features, Risk Factors, and Its Impact on Quality of Life and Sexual Health

Ooi Shin Yi et al. Indian J Dermatol. 2022 Mar-Apr.

Abstract

Background: Genital psoriasis is often under-recognized and the exact burden is unknown in Malaysia.

Objectives: To identify the prevalence of genital psoriasis, its clinical features, risk factors, and impact on quality of life and sexual health.

Methods: This prospective, observational study was conducted in the dermatology clinic of our hospital from 1st September 2020 until 31st March 2021, involving all adult patients with psoriasis. The genital examination was performed and the subjects were interviewed using questionnaires.

Results: A total of 262 patients were recruited, with a male to female ratio of 1.5:1 (mean age of 51 years old). They comprised 42.0% Chinese, followed by 36.6% of Malay, 21.4% of Indians and others. Up to 46.1% of patients had a current or history of genital psoriasis. The most common area involved for males was the scrotum (44.1%) and labia majora (62.5%) for female patients. Itching (79.2%) was the most frequent symptom encountered. Chinese patients had 2.67 times odd (CI 1.55-4.61) of having genital psoriasis compared to non-Chinese patients. Other independent risk factors included flexural involvement, male gender, and Type 1 psoriasis. Genital psoriasis was associated with greater impairment on quality of life and sexual health (mean total Dermatology Life Quality Index: 8.8 vs 6.5, P = 0.006), International Index of Erectile Function (mean: 48.5 vs 57.0, P = 0.011) and revised version of Female Sexual Distress Scales (mean: 20.7 vs 11.4, P = 0.022).

Conclusions: Genital psoriasis is common and it has a profound impact on patients.

Keywords: Dermatology life quality index; female sexual function index; genital psoriasis; international index of erectile function; quality of life; sexual dysfunction.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Distribution of topography of genital lesions among patients with genital psoriasis
Figure 2
Figure 2
Severe genital psoriasis with perigenital involvement in an Indian patient. (Fitzpatrick skin type V)
Figure 3
Figure 3
Typical appearance of genital psoriasis in a Chinese patient. (Fitzpatrick skin type III)

References

    1. Gibbs S. Skin disease and socioeconomic conditions in rural Africa: Tanzania. Int J Dermatol. 1996;35:633–9. - PubMed
    1. Danielsen K, Olsen AO, Wilsgaard T, Furberg AS. Is the prevalence of psoriasis increasing? A 30-year follow-up of a population-based cohort. Br J Dermatol. 2013;168:1303–10. - PubMed
    1. Robinson S, Tang MM, Ramalingam R, Voo SY, Kwan Z, Thevarajah S. The Tenth report of the Malaysian Psoriasis Registry 2007-2018, Kuala Lumpur, Malaysia. 2020
    1. Meeuwis KAP, Potts Bleakman A, van de Kerkhof PCM, Dutronc Y, Henneges C, Kornberg LJ, et al. Prevalence of genital psoriasis in patients with psoriasis. J Dermatol Treat. 2018;29:754–60. - PubMed
    1. Gottlieb AB, Kirby B, Ryan C, Naegeli A, Burge R, Potts Bleakman A, et al. The development of a patient-reported outcome measure for assessment of genital psoriasis symptoms: The Genital psoriasis symptoms scale (GPSS) Dermatol Ther (Heidelb) 2018;8:45–56. - PMC - PubMed