Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2022 Aug;11(8):2985-2989.
doi: 10.21037/tcr-21-2913.

Primary teratoma of the adrenal gland: a case report

Affiliations
Case Reports

Primary teratoma of the adrenal gland: a case report

Xiaocheng Ma et al. Transl Cancer Res. 2022 Aug.

Abstract

Background: Teratomas are unusual tumors derived from multiple germ layers but they usually arise from all three germ layers. Knowledge of this disease is still very limited because of its low incidence. Retroperitoneal teratomas are extremely rare neoplasms, especially adrenal teratomas, which frequently found to be large, cystic or cyst-solid lesions. Adrenal teratomas are easily confused with various benign or malignant tumors, such as myelolipomas, adenomas, and hamartomas.

Case description: In this case presentation, we report a rare case in which an adrenal gland mass without apparent discomfort was detected by abdominal computed tomography (CT) for 6 months in a 59-year-old female. Results from the patient's adrenal hormonal evaluation were normal. An abdominal enhanced CT scan revealed a heterogeneous mass in the right adrenal gland. The patient then underwent a laparoscopic right adrenalectomy and the lesion was diagnosed as mature teratoma through histopathological examination. The patient recovered well without any complications.

Conclusions: Based on our knowledge, surgical resection is the first-choice intervention for the diagnosis and treatment of mature teratoma. Open surgery is the preferred method for the large tumors, while the laparoscopic adrenalectomy can be a better option in the small one. The patient's prognosis is usually good after complete resection, but close follow-up is also recommended.

Keywords: Teratoma; adrenal; adrenalectomy; case report.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://tcr.amegroups.com/article/view/10.21037/tcr-21-2913/coif). The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
CT features of the mass in the right adrenal gland. CT scanning revealed a heterogeneous mass measuring 6 cm by 5 cm with a small cystic area, fat, and calcification. No obvious contrast enhancement was located in the right adrenal gland. CT, computed tomography.
Figure 2
Figure 2
Macroscopic and microscopic picture of the tumor. (A) Tumor specimen. Calcification, hair, and lipid can be seen in the teratoma; (B) pathological examination (H&E staining, ×200). H&E, hematoxylin and eosin.

Similar articles

References

    1. Gatcombe HG, Assikis V, Kooby D, et al. Primary retroperitoneal teratomas: a review of the literature. J Surg Oncol 2004;86:107-13. 10.1002/jso.20043 - DOI - PubMed
    1. Taori K, Rathod J, Deshmukh A, et al. Primary extragonadal retroperitoneal teratoma in an adult. Br J Radiol 2006;79:e120-2. 10.1259/bjr/33507627 - DOI - PubMed
    1. Polo JL, Villarejo PJ, Molina M, et al. Giant mature cystic teratoma of the adrenal region. AJR Am J Roentgenol 2004;183:837-8. 10.2214/ajr.183.3.1830837 - DOI - PubMed
    1. Grosfeld JL, Billmire DF. Teratomas in infancy and childhood. Curr Probl Cancer 1985;9:1-53. 10.1016/S0147-0272(85)80031-3 - DOI - PubMed
    1. McDougal WS, Wein AJ, Kavoussi LR, et al. editors. Campbell-Walsh Urology. 11 ed. Philadelphia: Elsevier Health Sciences 2015;Chapter III:Section 13.

Publication types