Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Sep;56(1):169-204.
doi: 10.1016/j.yasu.2022.02.011.

Is There a Place for Hyperbaric Oxygen Therapy?

Kinjal N Sethuraman  1 , Ryan Smolin  2 , Sharon Henry  3
Affiliations
Review

Is There a Place for Hyperbaric Oxygen Therapy?

Kinjal N Sethuraman et al. Adv Surg. 2022 Sep.

Abstract

Hyperbaric oxygen therapy (HBOT) involves treating patients by providing 100% oxygen through inhalation while inside a treatment pressurized chamber. The oxygen acts as a drug and the hyperbaric chamber as the dosing device. The effect of hyperbaric hyperoxia is dose dependent and, therefore, treatment depth and duration are important when considering its use. HBOT can either be the primary method of treatment or used adjunctively to medications or surgical techniques. The underpinning physiology is to bring oxygen-rich plasma to hypoxic tissue, preventing reperfusion injury, strengthening immune responsiveness, and encouraging new collagen deposition as well as endothelial cell formation.

Keywords: Hyperbaric chamber; Hyperbaric oxygen therapy; Hypoxia; Inhalation.

PubMed Disclaimer

Conflict of interest statement

Disclosure The authors have nothing to disclose.

LinkOut - more resources