Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Jun 9;3(4):415-421.
doi: 10.1016/j.hroo.2022.05.010. eCollection 2022 Aug.

The association of racial differences with in-hospital outcomes of patients admitted for sinus node dysfunction

Affiliations

The association of racial differences with in-hospital outcomes of patients admitted for sinus node dysfunction

Michael Albosta et al. Heart Rhythm O2. .

Abstract

Background: The impact of race and its related social determinants of health on cardiovascular disease outcomes has been well documented. However, limited data exist regarding the association of race with in-hospital outcomes in patients admitted for sinus node dysfunction (SND).

Objective: To evaluate whether racial disparities exist in outcomes for patients hospitalized with a primary diagnosis of SND.

Methods: The National Inpatient Sample was queried from 2011 to 2018 for relevant ICD-9 and ICD-10 diagnosis and procedure codes. Baseline characteristics and in-hospital outcomes in patients with a primary diagnosis of SND were compared among White and non-White patients. A multivariate logistic regression model was used to adjust for potential confounding factors and statistically significant comorbidities between both cohorts.

Results: We identified 655,139 persons admitted with a primary diagnosis of SND, 520,926 (79.5%) of whom were White. Non-White patients had significantly higher all-cause mortality, length of stay, and total hospital cost. There were lower odds of pacemaker insertion (adjusted odds ratio [aOR] 1.13 [95% confidence interval (CI) 1.11-1.15]), temporary transvenous pacing (aOR 1.15 [95% CI 1.11-1.22]), and cardioversion (aOR 1.50 [95% CI 1.42-1.58]) in non-White patients. A subgroup analysis was performed and non-Hispanic Black race was predictive of a decreased odds of pacemaker insertion, cardioversion/defibrillation, and temporary transvenous pacing.

Conclusion: Significant differences of in-hospital outcomes exist between White and non-White patients with SND. These findings appeared to be primarily driven by disparities in non-Hispanic Black patients. Increased recognition and focused efforts to mitigate these disparities will improve the care of underrepresented populations treated for SND.

Keywords: Arrhythmia; Cardioversion; Defibrillation; Pacemaker; Racial disparities; Sick sinus syndrome; Sinus node dysfunction.

PubMed Disclaimer

Figures

Figure 1
Figure 1
In-hospital mortality in patients according to race.
Figure 2
Figure 2
Pacemaker insertion in patients according to race.
Figure 3
Figure 3
Temporary transvenous pacing in patients according to race.
Figure 4
Figure 4
Incidence of cardioversion/defibrillation in patients according to race.

References

    1. Jensen P.N., Gronroos N.N., Chen L.Y., et al. Incidence of and risk factors for sick sinus syndrome in the general population. J Am Coll Cardiol. 2014;64:531–538. - PMC - PubMed
    1. John R.M., Kumar S. Sinus node and atrial arrhythmias. Circulation. 2016;133:1892–1900. - PubMed
    1. Kusumoto F.M., Schoenfeld M.H., Barrett C., et al. 2018 ACC/AHA/HRS guideline on the evaluation and management of patients with bradycardia and cardiac conduction delay: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society [published correction appears in Circulation 2019;140:e506–e508] Circulation. 2019;140:e382–e482. - PubMed
    1. Bernstein A.D., Parsonnet V. Survey of cardiac pacing and defibrillation in the United States in 1993. Am J Cardiol. 1996;78:187–196. - PubMed
    1. Bernstein A.D., Parsonnet V. Survey of cardiac pacing and implanted defibrillator practice patterns in the United States in 1997. Pacing Clin Electrophysiol. 2001;24:842–855. - PubMed

LinkOut - more resources