Cultural evolution may influence heritability by shaping assortative mating

Abstract

Uchiyama et al. productively discuss how culture can influence genetic heritability and, by modifying environmental conditions, limit the generalizability of genome-wide association studies (GWASs). Here, we supplement their account by highlighting how recent changes in culture and institutions in industrialized, westernized societies - such as increased female workforce participation - may have increased assortative mating. This alters the distribution of genotypes themselves, increasing heritability and phenotypic variance, and may be detectable using the latest methods.