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Case Reports
. 2022 Dec 1;49(12):855-857.
doi: 10.1097/OLQ.0000000000001700. Epub 2022 Sep 7.

Report: A Pox Presenting Without Pox

Ellora Karmarkar  1 , Eden E Altwies  2 , Russom Desta  3 , Alwiya M Ahmed  3 , Epiphany Nick  2 , Maria Amoreth R Gozo  4 , Anna L Cogen  4 , Gabriela Uribe  5 , Steven Disharoon  3 , W Conrad Liles  1 , Sylvia M LaCourse
Affiliations
Case Reports

Report: A Pox Presenting Without Pox

Ellora Karmarkar et al. Sex Transm Dis. .

Abstract

A man with virally suppressed human immunodeficiency virus (HIV) presented with an erythematous, morbilliform rash without pustules in the setting of fever, fatigue, and myalgias after recent travel to Mexico and Puerto Rico. He was diagnosed with nonvariola orthopoxvirus (monkeypox) infection. This case report highlights an atypical presentation in the 2022 outbreak.

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Conflict of interest statement

Conflicts of Interest: None declared.

Figures

Figure 1:
Figure 1:. Evolution of rash in a patient with non-variola orthopoxvirus infection.
(A, B) Initial presentation with diffuse morbilliform rash and penile papule. (C) Hospital day 2 with new abdominal lesion. (D) Hospital day 3 with evolution and umbilication of back lesion.
Figure 2:
Figure 2:
Biopsy demonstrating eosinophilic cytoplasmic inclusion bodies and ballooning degeneration. Pathology image courtesy of Drs. Ata Moshiri and Martin Dittmer, University of Washington Department of Pathology.
See this image and copyright information in PMC

References

    1. “2022 Monkeypox Outbreak : Global Trends”. World Health Organization. Geneva, Switzerland. Accessed August 18, 2022. https://worldhealthorg.shinyapps.io/mpx_global/
    1. “Monkeypox: 2022 US Map and Case Count.” Centers for Disease Control and Prevention. Atlanta, Georgia. Accessed August 18, 2022. https://www.cdc.gov/poxvirus/monkeypox/response/2022/us-map.html
    1. Minhaj FS, Ogale YP, Whitehill F, et al. Monkeypox Outbreak — Nine States, May 2022. MMWR Morb Mortal Wkly Rep 2022;71:764–769. DOI: 10.15585/mmwr.mm7123e1. - DOI - PMC - PubMed
    1. Thornhill J, Barkati S, Walmsley S, et al. Monkeypox virus infection in Humans across 16 countries—April–June 2022. N Engl J Med. 2022. Jul 21. doi: 10.1056/NEJMoa2207323. Epub ahead of print. - DOI - PubMed
    1. Lapa D, Carletti F, Mazzotta V, et al. Monkeypox virus isolation from a semen sample collected in the early phase of infection in a patient with prolonged seminal viral shedding. Lancet Infect Dis. August 2022. doi: 10.1016/S1473-3099(22)00513-8: - DOI - PMC - PubMed

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