Bacterial immunity: Mobile genetic elements are hotspots for defence systems
- PMID: 36099898
- DOI: 10.1016/j.cub.2022.07.075
Bacterial immunity: Mobile genetic elements are hotspots for defence systems
Abstract
A new study reports that phage-inducible chromosomal islands (PICIs) are hotspots of defence systems against phages, other PICIs and plasmids. This discovery highlights how competition between mobile genetic elements shapes bacterial defence gene repertoires and helps to better understand how defence systems are exchanged among bacteria.
Copyright © 2022 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests The authors declare no competing interests.
Comment on
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Bacteriophages benefit from mobilizing pathogenicity islands encoding immune systems against competitors.Cell. 2022 Aug 18;185(17):3248-3262.e20. doi: 10.1016/j.cell.2022.07.014. Cell. 2022. PMID: 35985290
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