Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022;22(3):162-167.
doi: 10.2174/1871529X22666220913122046.

The Association Between Hematologic Indices with TIMI Flow in STEMI Patients who Undergo Primary Percutaneous Coronary Intervention

Saeed Alipour Parsa  1 , Saeed Nourian  1 , Morteza Safi  1 , Mohammad Hasan Namazi  1 , Habib Saadat  1 , Hossein Vakili  1 , Vahid Eslami  1 , Ayoub Salehi  1 , Farshid Heidarpour Kiaee  1 , Nasim Sohrabifar  1 , Isa Khaheshi  1
Affiliations

The Association Between Hematologic Indices with TIMI Flow in STEMI Patients who Undergo Primary Percutaneous Coronary Intervention

Saeed Alipour Parsa et al. Cardiovasc Hematol Disord Drug Targets. 2022.

Abstract

Background: The Primary Percutaneous Coronary Intervention (PPCI) is the preferred therapeutic strategy for patients who experienced ST-Elevation Myocardial Infarction (STEMI).

Objective: We aimed to evaluate the association of hematological indices, including hemoglobin level, platelets, White Blood Cells (WBCs) count, and MPV before PPCI with the TIMI grade flow after PPCI.

Methods: STEMI patients who experienced PPCI were included in the present retrospective crosssectional study. Then participants were divided into three groups based on their post-procedural TIMI flow grades. Demographic data and hematologic indices of patients before PPCI were collected and their association with the TIMI grade flow after PPCI was evaluated. To compare the quantitative and qualitative variables, chi-square and t-tests were performed, respectively.

Results: We found that elevated levels of hemoglobin and decreased levels of MPV had a significant association with an advanced grade of TIMI flow. Interestingly, in the normal range, there was a significant association between higher platelet count and TIMI-flow grade 1. Besides, TIMI flow grades 2 and 3 had a significant association with low and moderate platelets count, respectively.

Conclusion: In conclusion, evaluating MPV, platelets, and hemoglobin levels before PPCI as easy and accessible parameters may be able to identify high-risk STEMI patients undergoing PPCI.

Keywords: PPCI; STEMI; TIMI-flow grade; adverse outcome; hematologic indices.; prognosis.

PubMed Disclaimer

References

    1. O’Gara P.T.; Kushner F.G.; Ascheim D.D.; Casey D.E.; Chung M.K.; de Lemos J.A.; Ettinger S.M.; Fang J.C.; Fesmire F.M.; Franklin B.A.; Granger C.B.; Krumholz H.M.; Linderbaum J.A.; Morrow D.A.; Newby L.K.; Ornato J.P.; Ou N.; Radford M.J.; Tamis-Holland J.E.; Tommaso C.L.; Tracy C.M.; Woo Y.J.; Zhao D.X.; 2013 ACCF/AHA Guideline for the management of ST-elevation myocardial infarction: Executive summary: A report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines. Catheter Cardiovasc Interv 2013,82(1),E1-E27 - DOI - PubMed
    1. Trost J.C.; Lange R.A.; Treatment of acute coronary syndrome. Crit Care Med 2012,40(6),1939-1945 - DOI - PubMed
    1. Vogel B.; Claessen B.E.; Arnold S.V.; Chan D.; Cohen D.J.; Giannitsis E.; Gibson C.M.; Goto S.; Katus H.A.; Kerneis M.; Kimura T.; Kunadian V.; Pinto D.S.; Shiomi H.; Spertus J.A.; Steg P.G.; Mehran R.; ST-segment elevation myocardial infarction. Nat Rev Dis Primers 2019,5(1),39 - DOI - PubMed
    1. Lacey B.; Herrington W.G.; Preiss D.; Lewington S.; Armitage J.; The role of emerging risk factors in cardiovascular outcomes. Curr Atheroscler Rep 2017,19(6),28 - DOI - PubMed
    1. Piepoli M.F.; Hoes A.W.; Agewall S.; Albus C.; Brotons C.; Catapano A.L.; Cooney M.T.; Corrà U.; Cosyns B.; Deaton C.; Graham I.; Hall M.S.; Hobbs F.D.R.; Løchen M.L.; Löllgen H.; Marques-Vidal P.; Perk J.; Prescott E.; Redon J.; Richter D.J.; Sattar N.; Smulders Y.; Tiberi M.; van der Worp H.B.; van Dis I.; Verschuren W.M.M.; Binno S.; 2016 European Guidelines on cardiovascular disease prevention in clinical practice. Eur Heart J 2016,37(29),2315-2381 - DOI - PubMed

LinkOut - more resources