Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Nov 1;41(11):e453-e455.
doi: 10.1097/INF.0000000000003688. Epub 2022 Aug 31.

Epidemiology of Exposures, Preceding Illness and Testing History in Children With Multisystem Inflammatory Syndrome in Children in the First 18 Months of the COVID-19 Pandemic, Los Angeles County, California

Caitlin N Newhouse  1   2 , Lauren Finn  1 , Candace M Gragnani  1   2 , Susan Hathaway  1 , Denise Nunez  1   2 , Jason Malenfant  1   2 , Priyanka Fernandes  1   2 , Moon Kim  1 , Dawn Terashita  1 , Sharon Balter  1
Affiliations

Epidemiology of Exposures, Preceding Illness and Testing History in Children With Multisystem Inflammatory Syndrome in Children in the First 18 Months of the COVID-19 Pandemic, Los Angeles County, California

Caitlin N Newhouse et al. Pediatr Infect Dis J. .

Abstract

We describe the epidemiology of COVID-19 exposure, preceding illness, and SARS-CoV-2 testing in a large population with MIS-C during the first 18 months of the COVID-19 pandemic. The majority of cases had exposure, preceding illness, or positive SARS-CoV-2 testing 4-8 weeks before MIS-C onset. Serology can help establish epidemiological link to COVID-19 when past infection or exposure are unknown.

PubMed Disclaimer

Conflict of interest statement

The authors have no funding or conflicts of interest to disclose.

Figures

FIGURE 1.
FIGURE 1.
Overlap in epidemiologic link to SARS-CoV-2 in reported MIS-C cases.
See this image and copyright information in PMC

References

    1. Belay ED, Abrams J, Oster ME, et al. . Trends in geographic and temporal distribution of US children with multisystem inflammatory syndrome during the COVID-19 pandemic. JAMA Pediatr. 2021;30333:1–9. - PMC - PubMed
    1. Dufort EM, Koumans EH, Chow EJ, et al. . Multisystem inflammatory syndrome in children in New York State. N Engl J Med. 2020;383:347–358. doi:10.1056/NEJMoa2021756. - PMC - PubMed
    1. US Centers for Disease Control and Prevention (CDC). COVID Data Tracker: Health Department-Reported Cases of Multisystem Inflammatory Syndrome in Children (MIS-C) in the United States. Available at: https://covid.cdc.gov/covid-data-tracker/#mis-national-surveillance. 2021. Accessed October 1, 2021.
    1. Cirks BT, Rowe SJ, Jiang SY, et al. . 16 Weeks Later: Expanding the Risk Period for MIS-C. J Pediatric Infect Dis Soc. 2021;10:686–690. - PMC - PubMed
    1. U.S. Food and Drug Administration (FDA). FDA Authorizes Pfizer-BioNTech COVID-19 Vaccine for Emergency Use in Children 5 through 11 Years of Age. 2021. Available at: https://www.fda.gov/news-events/press-announcements/fda-authorizes-pfize.... Accessed November 1, 2021.

Supplementary concepts