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Comment
. 2022 Sep 14;7(1):320.
doi: 10.1038/s41392-022-01171-z.

SLC7A11: a new regulator in diabetic wound healing

Shunli Rui  1 , Yu Ma  2 , Wuquan Deng  3
Affiliations
Comment

SLC7A11: a new regulator in diabetic wound healing

Shunli Rui et al. Signal Transduct Target Ther. .
No abstract available

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Boosting efferocytosis improves diabetic wound healing via targeting SLC7A11 in dendritic cells (DCs). a SLC7A11 acts as brake on DC efferocytosis, which was revealed by RNA-seq in DCs during efferocytosis. b Interfering with SLC7A11 function affected wound healing dynamics by erastin co-administering early-stage apoptotic cells in vivo. c Efferocytosis in DCs enhanced via glycogenolysis with inhibition or knockout of SLC7A11 in vitro. d SLC7A11 inhibition at the wound site can boost diabetic wound healing by improving apoptotic cell clearance and GDF15 secretion. Created with BioRender.com
See this image and copyright information in PMC

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References

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