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. 2022 Dec;42(12):1686-1694.
doi: 10.1038/s41372-022-01505-3. Epub 2022 Sep 14.

Hospital variation in extremely preterm birth

Gregory P Goldstein  1 , Peiyi Kan  2 , Ciaran S Phibbs  2   3 , Elliott Main  4   5 , Gary M Shaw #  2 , Henry C Lee #  2   6
Affiliations

Hospital variation in extremely preterm birth

Gregory P Goldstein et al. J Perinatol. 2022 Dec.

Abstract

Objective: Given that regionalization of extremely preterm births (EPTBs) is associated with improved infant outcomes, we assessed between-hospital variation in EPTB stratified by hospital level of neonatal care, and determined the proportion of variance explained by differences in maternal and hospital factors.

Study design: We assessed 7,046,253 births in California from 1997 to 2011, using hospital discharge, birth, and death certificate data. We estimated the association between maternal and hospital factors and EPTB using multivariable regression, calculated hospital-specific EPTB frequencies, and estimated between-hospital variances and median odds ratios, stratified by hospital level of care.

Result: Hospital frequencies of EPTB ranged from 0% to 2.5%. Between-hospital EPTB frequencies varied substantially, despite stratifying by hospital level of care and accounting for confounding factors.

Conclusion: Our results demonstrate differences in EPTBs among hospitals with level 1 and 2 neonatal care, an area to target for future research and quality improvement.

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References

    1. Lau C, Ambalavanan N, Chakraborty H, Wingate MS, Carlo WA. Extremely low birth weight and infant mortality rates in the United States. Pediatrics. 2013;131:855–60. - DOI - PubMed
    1. Hamilton BE, Hoyert DL, Martin JA, Strobino DM, Guyer B. Annual summary of vital statistics: 2010-2011. Pediatrics. 2013;131:548–58. - DOI - PubMed
    1. Stoll BJ, Hansen NI, Bell EF, Walsh MC, Carlo WA, Shankaran S, et al. Trends in care practices, morbidity, and mortality of extremely preterm neonates, 1993-2012. JAMA. 2015;314:1039–51. - DOI - PubMed - PMC
    1. Taylor HG, Klein N, Minich NM, Hack M. Long-term family outcomes for children with very low birth weights. Arch Pediatr Adolesc Med. 2001;155:155–61. - DOI - PubMed
    1. Lakshmanan A, Agni M, Lieu T, Fleegler E, Kipke M, Friedlich PS, et al. The impact of preterm birth <37 weeks on parents and families: a cross-sectional study in the 2 years after discharge from the neonatal intensive care unit. Health Qual Life Outcomes. 2017;15:38. - DOI - PubMed - PMC

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