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Comment
. 2022 Sep 14;30(9):1196-1198.
doi: 10.1016/j.chom.2022.08.012.

A lung pathobiont story: Thinking outside the Koch's postulate box

Shivani Singh  1 , Leopoldo N Segal  2
Affiliations
Free article
Comment

A lung pathobiont story: Thinking outside the Koch's postulate box

Shivani Singh et al. Cell Host Microbe. .
Free article

Abstract

Li et al., demonstrate how Neisseria spp., thought to be a commensal, can play a pathogenic role in bronchiectasis. Here, we discuss how our thinking has evolved from the classical Koch's postulates to a complex network of microbial-host interactions and their role in disease pathogenesis.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

Comment on

  • Neisseria species as pathobionts in bronchiectasis.
    Li L, Mac Aogáin M, Xu T, Jaggi TK, Chan LLY, Qu J, Wei L, Liao S, Cheng HS, Keir HR, Dicker AJ, Tan KS, De Yun W, Koh MS, Ong TH, Lim AYH, Abisheganaden JA, Low TB, Hassan TM, Long X, Wark PAB, Oliver B, Drautz-Moses DI, Schuster SC, Tan NS, Fang M, Chalmers JD, Chotirmall SH. Li L, et al. Cell Host Microbe. 2022 Sep 14;30(9):1311-1327.e8. doi: 10.1016/j.chom.2022.08.005. Cell Host Microbe. 2022. PMID: 36108613

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