[Nonspecific suppressive effect of Ehrlich tumor ascitic fluid on transplantation immunity]
[Article in
Russian]
- PMID: 361103
Item in Clipboard
[Nonspecific suppressive effect of Ehrlich tumor ascitic fluid on transplantation immunity]
[Article in
Russian]
Biull Eksp Biol Med.
1978 Oct.
Abstract
The influence of syngeneic Ehrlich ascites tumour fluid on the survival of allogeneic skin allografts was investigated on CC57BR mice. A 3--4-day delay of the allograft rejection in mice injected with ascitic fluid was revealed. Preliminary transplantation of such allograft to mice with Ehrlich tumour produced no intensification of the immunodepressive action of the ascites fluid obtained from them. The data obtained indicated the preferential significance of the antigen-independent immunosuppressive factors of ascites tumour fluid in the suppression of the transplantation immunity in vivo.
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