Surface behaviors of droplet manipulation in microfluidics devices
- PMID: 36113310
- DOI: 10.1016/j.cis.2022.102770
Surface behaviors of droplet manipulation in microfluidics devices
Abstract
In recent years, the rapid development of microfluidic technology has caused a revolutionary impact in the fields of chemistry, medicine, and life sciences. Also, droplet control is one of the most important technologies in the field of microfluidics. In order to achieve different degrees of droplet transport, the dynamic balance of the competing processes of droplet driving force and fluid resistance should be controlled to achieve good selectivity of droplet transport. Here, we focus on the principles of droplet transport in microfluidic devices, including the driving forces for droplet transport in fluids and the effects of transport properties on droplet transport. After that, the effects of external fields on the directional transport of droplets and the advantages and disadvantages of each external field in droplet transport are discussed in detail. Finally, the applications and challenges of droplet microfluidics in chemical, biomedical, and mechanical systems are comprehensively introduced.
Keywords: Droplet; Manipulation; Microfluidics; Surface.
Copyright © 2022 Elsevier B.V. All rights reserved.
Conflict of interest statement
Declaration of Competing Interest There are no conflicts to declare.
Similar articles
-
Self-powered droplet manipulation system for microfluidics based on triboelectric nanogenerator harvesting rotary energy.Lab Chip. 2021 Jan 21;21(2):284-295. doi: 10.1039/d0lc00994f. Epub 2021 Jan 13. Lab Chip. 2021. PMID: 33439205
-
Single-cell droplet microfluidics for biomedical applications.Analyst. 2022 May 30;147(11):2294-2316. doi: 10.1039/d1an02321g. Analyst. 2022. PMID: 35506869 Review.
-
Materials and methods for droplet microfluidic device fabrication.Lab Chip. 2022 Mar 1;22(5):859-875. doi: 10.1039/d1lc00836f. Lab Chip. 2022. PMID: 35170611 Free PMC article. Review.
-
Taking advantage of reduced droplet-surface interaction to optimize transport of bioanalytes in digital microfluidics.J Vis Exp. 2014 Nov 10;(93):e52091. doi: 10.3791/52091. J Vis Exp. 2014. PMID: 25407533 Free PMC article.
-
Hybrid Digital-Droplet Microfluidic Chip for Applications in Droplet Digital Nucleic Acid Amplification: Design, Fabrication and Characterization.Sensors (Basel). 2023 May 20;23(10):4927. doi: 10.3390/s23104927. Sensors (Basel). 2023. PMID: 37430841 Free PMC article.
Cited by
-
Recent Trends of Microfluidics in Food Science and Technology: Fabrications and Applications.Foods. 2022 Nov 20;11(22):3727. doi: 10.3390/foods11223727. Foods. 2022. PMID: 36429319 Free PMC article. Review.
-
A comprehensive review on electrically modulated transport of soft, multiphase systems in microflow: Perspectives on drops and vesicles.Biomicrofluidics. 2025 Jun 4;19(3):031503. doi: 10.1063/5.0254950. eCollection 2025 May. Biomicrofluidics. 2025. PMID: 40488123 Review.
-
A Noninvasive Menstrual Blood-Based Diagnostic Platform for Endometriosis Using Digital Droplet Enzyme-Linked Immunosorbent Assay and Single-Cell RNA Sequencing.Research (Wash D C). 2025 Apr 1;8:0652. doi: 10.34133/research.0652. eCollection 2025. Research (Wash D C). 2025. PMID: 40171018 Free PMC article.
-
Microfluidics-Based Microcarriers for Live-Cell Delivery.Adv Sci (Weinh). 2025 May;12(18):e2414410. doi: 10.1002/advs.202414410. Epub 2025 Apr 4. Adv Sci (Weinh). 2025. PMID: 40184613 Free PMC article. Review.
-
An Open-Type Crossflow Microfluidic Chip for Deformable Droplet Separation Driven by a Centrifugal Field.Micromachines (Basel). 2025 Jun 30;16(7):774. doi: 10.3390/mi16070774. Micromachines (Basel). 2025. PMID: 40731682 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources