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. 2022 Jan 10;14(3):260-264.
doi: 10.1055/s-0041-1741438. eCollection 2022 Sep.

An Update on Secondary Bacterial and Fungal Infections and Their Antimicrobial Resistance Pattern (AMR) in COVID-19 Confirmed Patients

Sushma Yadav Boorgula  1 , Sadhana Yelamanchili  1 , Pragathi Kottapalli  1 , Mohini D Naga  1
Affiliations

An Update on Secondary Bacterial and Fungal Infections and Their Antimicrobial Resistance Pattern (AMR) in COVID-19 Confirmed Patients

Sushma Yadav Boorgula et al. J Lab Physicians. .

Abstract

Introduction Since coronavirus disease 2019 (COVID-19) has limited treatment options, concern has been raised over secondary infections and antimicrobial resistance (AMR) patterns. It has been observed that patients who were infected with COVID-19 were predisposed to develop secondary infections. The purpose of the study is to ascertain the prevalence of the bacterial and fungal coinfections in COVID-19 patients, and also to assess the AMR patterns in the obtained isolates. Methods We have studied 200 clinical samples obtained from 122 COVID-19 positive patients. Pathogens were identified using Vitek 2 system. The demographic and clinical patterns were also observed. Results A total of 122 patients developed secondary infections. Patients aged more than 40 years were majorly affected ( p -value < 0.0001). Respiratory samples ( n = 96) were predominant. Klebsiella pneumoniae ( n = 68) was the most common pathogen isolated followed by Acinetobacter baumannii ( n = 54) and an overall 6% rise in the Carbapenem resistance was observed in the isolates. Conclusion To contain the secondary infections in COVID-19 patients, it is imperative to adhere to antimicrobial stewardship program and timely revise the empirical antibiotic policy.

Keywords: antimicrobial resistance; central line associated bloodstream infections; coagulase-negative staphylococcus.

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Conflict of interest statement

Conflict of Interest None.

Figures

Fig. 1
Fig. 1
Bacteria and fungus profile.
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