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Case Reports
. 2022 Sep 6:30:e01615.
doi: 10.1016/j.idcr.2022.e01615. eCollection 2022.

Successful treatment of rhino-cerebral mucormycosis with dual antifungal therapy and minimal surgical debridement

Lauren Bougioukas  1 , Cindy D Noyes  2   3 , Katherine Peterson  2 , Lindsay M Smith  2   3 , Andrew J Hale  2   3
Affiliations
Case Reports

Successful treatment of rhino-cerebral mucormycosis with dual antifungal therapy and minimal surgical debridement

Lauren Bougioukas et al. IDCases. .

Abstract

The authors report the case of a 42-year-old female with history of type I diabetes mellitus and recent episode of diabetic ketoacidosis who presented with symptoms of epistaxis, gastrointestinal upset, hyperglycemia, confusion, and a cough. She was found to have rhino-cerebral mucormycosis with associated multi-focal strokes and a left internal carotid artery pseudoaneurysm. Her infection was successfully treated with dual-antifungal therapy consisting of liposomal amphotericin B and isavuconazole, and required only minimal surgical debridement.

Keywords: Amphotericin B; Intracerebral; Invasive fungal infection; Isavuconazole; Liposomal amphotericin B; Mucormycosis; Rhino-cerebral mucormycosis.

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Conflict of interest statement

None of the authors report any conflicts of interest.

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