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. 2022 Dec 1;176(12):1260-1261.
doi: 10.1001/jamapediatrics.2022.3251.

Antenatal Steroid Exposure Among Term Newborns

Taylor S Freret  1 , Kaitlyn E James  1 , Alexander Melamed  2 , Cynthia Gyamfi-Bannerman  3 , Anjali J Kaimal  1 , Mark A Clapp  1
Affiliations

Antenatal Steroid Exposure Among Term Newborns

Taylor S Freret et al. JAMA Pediatr. .
No abstract available

Plain language summary

This cross-sectional study evaluates the association between dissemination of the Antenatal Late Preterm Steroid trial and changes in steroid exposure among term newborns.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Melamed reported receiving grants from the National Center for Advancing Translational Sciences, the National Cancer Institute, and the Conquer Cancer–The ASCO Foundation outside the submitted work. Dr Gyamfi-Bannerman reported receiving grants from the National Heart, Lung, and Blood Institute and the National Institute on Minority Health and Health Disparities and receiving personal fees from Medela and Hologic for lectures outside the submitted work. Dr Clapp reported receiving grants from the American Association of Obstetricians and Gynecologists Foundation and the Risk Management Foundation of the Harvard Medical Institutions, Inc., and serving as a Medical Advisory Board member with and holding private equity in Delflina Health outside the submitted work. No other disclosures were reported.

Figures

Figure 1.
Figure 1.. Flowchart of Inclusion and Exclusion Criteria
ALPS trial indicates Antenatal Late Preterm Steroid trial.
Figure 2.
Figure 2.. Expected and Observed Antenatal Steroid Exposure Rates Among Term Newborns
Models were controlled for gestational age at delivery, maternal age, race, Hispanic ethnicity, primary payer for delivery admission, and delivery practitioner type. Race and Hispanic ethnicity were collected by self-report from birth certificate data and were reported to account for potential variation in steroid administration rates in different groups. Markers indicate estimates for monthly steroid administration; vertical lines, 95% CIs; shading, Antenatal Late Preterm Steroid trial dissemination period; solid lines, observed trends; and dashed line, expected trend.
See this image and copyright information in PMC

Comment in

References

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