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Review

The Soil Habitat and Considerations for Synthetic Biology

Robyn A. Barbato  1
Benjamin D. Trump  1 , Marie-Valentine Florin  2 , Edward Perkins  3 , Igor Linkov  1
, editors.
In: Emerging Threats of Synthetic Biology and Biotechnology: Addressing Security and Resilience Issues [Internet]. Dordrecht (DE): Springer; 2021. Chapter 11.
.
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Review

The Soil Habitat and Considerations for Synthetic Biology

Robyn A. Barbato.
Free Books & Documents

Excerpt

Microorganisms serve as agents for synthetic biology. It certain instances, the technology is reliant on survival of the genetically-altered microorganism in the natural environment. This chapter offers insight into the soil system to improve the performance of genetically-altered microorganisms in the natural environment. This chapter covers the soil system, the fitness of genetically altered organisms, and considerations for their survival and proliferation in nature. This chapter does not discuss the ecological consequences of survival in the natural environment or the regulatory considerations to distribute a genetically-altered organism in the environment. In addition to regulatory approval, both considerations should be critically reviewed before a genetically-altered organism is distributed in the environment.

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References

    1. Borken W, Matzner E (2009) Reappraisal of drying and wetting effects on C and N mineralization and fluxes in soils. Glob Chang Biol 15(4):808–824
    1. Brophy JAN, Triassi AJ, Adams BL, Renberg RL, Stratis-Cullum DN, Grossman AD, Voight CA (2018) Engineered integrative and conjugative elements for efficient and inducible DNA transfer to undomesticated bacteria. Nat Microbiol 3:1043–1053 - PubMed
    1. Danchin A (2012) Scaling up synthetic biology: do not forget the chassis. FEBS Lett 23586:2129–2137 - PubMed
    1. Fierer N, Schimel JP, Holden PA (2003) Influence of drying-rewetting frequency on soil bacterial community structure. Microb Ecol 45(1):63–71 - PubMed
    1. Fierer N, Colman BP, Schimel JP, Jackson RB (2006) Predicting the temperature dependence of microbial respiration in soil: a continental-scale analysis. Glob Biogeochem Cycles 20(3):GB3026

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