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Review

Synthetic Biology Brings New Challenges to Managing Biosecurity and Biosafety

In: Emerging Threats of Synthetic Biology and Biotechnology: Addressing Security and Resilience Issues [Internet]. Dordrecht (DE): Springer; 2021. Chapter 8.
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Review

Synthetic Biology Brings New Challenges to Managing Biosecurity and Biosafety

Andrew Jin et al.
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Excerpt

Novel biology technologies like gene editing and genetic engineering are creating a proliferation of breakthroughs in engineered biological systems that will change our world in areas ranging from medicine, to textiles, to energy. New developments in gene editing technologies, especially CRISPR-Cas9, have shown early signs of extraordinary potential in a variety of fields, including from basic research, applied biotechnology, and biomedical research. While the possibility of directly targeting and modifying genomic sequences in almost all eukaryotic cells could significantly improve standards of living, these technologies have the potential to pose serious biological hazards.

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References

    1. Bakanidze L, Imnadze P, Perkins D (2010) Biosafety and biosecurity as essential pillars of international health security and cross-cutting elements of biological nonproliferation. BMC Public Health BioMed Central. https://doi.org/10.1186/1471-2458-10-S1-S12 - DOI - PMC - PubMed
    1. Chan CTY, Lee JW, Ewen Cameron D, Bashor CJ, Collins JJ (2016) ‘Deadman’ and ‘passcode’ microbial kill switches for bacterial containment. Nat Chem Biol 12(2):82–86. https://doi.org/10.1038/nchembio.1979 - DOI - PMC - PubMed
    1. Dyal JW, Grant MP, Broadwater K, Adam Bjork MA, Waltenburg JD, Gibbins CH et al (2020) COVID-19 among Workers in Meat and Poultry Processing Facilities ― 19 states, April 2020. Morb Mortal Wkly Rep 69(18):557–561. https://doi.org/10.15585/mmwr.mm6918e3 - DOI - PubMed
    1. Ebi KL, Semenza JC (2008) Community-based adaptation to the health impacts of climate change. Am J Prev Med. Elsevier Inc. https://doi.org/10.1016/j.amepre.2008.08.018 - DOI - PubMed
    1. Evans NG (2015) Dual-use decision making: relational and positional issues. Monash Bioeth Rev. https://doi.org/10.1007/s40592-015-0026-y - DOI - PMC - PubMed

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