Organic Molecules Containing N, S and O Heteroatoms as Sensors for the Detection of Hg(II) Ion; Coordination and Efficiency toward Detection

Abstract

Rapid detection of potentially toxic heavy metals like Hg(II) has attracted great attention in the last few decades due to the importance to maintain a safe and sustainable environment for human beings. Coordination chemistry and concepts therein, play an important role in the detection of Hg(II). Size, charge, and nature of the donor atom and the respective cation (metal ion), are crucial in selective interactions between the sensor and metal ions. The sensors designed for the purpose, coordinate to Hg(II) ion through various donor sites, coordination causes a change in the electron density in organic molecules and results in either visible color change or enhancing/quenching fluorescence intensity. Since Hg(II) is soft metal, with d¹⁰ electron system, so majority of the sensors have soft donor sites which prefer to coordinate with Hg(II). Oxygen is also present in some chelating ligands which is least preferred coordination site, due to its hard nature. There are several reports of replacing other ligating sites by sulfur for enhanced mercury sensing. In some cases, desulfurization is being detected as clear change in spectral behavior during the sensing process. Efforts are still in progress to design and introduce a sensor with utmost sensitivity and selectivity. In this review, we made an attempt to explain the coordination aspects of Hg(II) detectors, reasons for poor efficiency and possible suggestions to improve the selection criterion of various compounds. It will help researchers to know about important concepts in designing more sensitive and selective sensors for detection of Hg(II) in environmental and biological samples.

Keywords: Coordination chemistry; Hg(II) detectors; chemosensing; colorimetric detection of Hg ions; single molecules detectors.