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Review
. 2022 Oct 28;85(10):2395-2398.
doi: 10.1021/acs.jnatprod.2c00602. Epub 2022 Sep 19.

Crannenols A-D, Sesquiterpenoids from the Irish Deep-Sea Soft Coral Acanella arbuscula

Joshua T Welsch  1 , Ryan M Young  2 , A Louise Allcock  2 , Mark P Johnson  2 , Bill J Baker  1
Affiliations
Review

Crannenols A-D, Sesquiterpenoids from the Irish Deep-Sea Soft Coral Acanella arbuscula

Joshua T Welsch et al. J Nat Prod. .

Abstract

Four undescribed sesquiterpenoids, crannenols A-D (1-4), have been isolated from CHCl2 and MeOH extracts of the deep-sea bamboo coral Acanella arbuscula. The corals were collected from a submarine canyon on the edge of Ireland's Porcupine Bank via a remotely operated vehicle. The structure elucidation of these (Z,E)-α-farnesene derivatives was achieved using a combination of 1D and 2D NMR, electron impact (1, 2), and electrospray ionization (3, 4) mass spectrometry.

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Conflict of interest statement

The authors declare no competing financial interest.

Figures

Figure 1
Figure 1
Key HMBC (blue →) and COSY (thick ―) correlations (A) and key NOESY (red ↔) correlations (B) establishing the configuration of crannenol A (1).
See this image and copyright information in PMC

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