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. 2022 Dec;43(12):998-1000.
doi: 10.1016/j.tips.2022.08.010. Epub 2022 Sep 7.

Lessons from COVID-19 to increase opioid vaccine acceptance

Roxana Damiescu  1 , Mita Banerjee  2 , Norbert W Paul  3 , Thomas Efferth  4
Affiliations

Lessons from COVID-19 to increase opioid vaccine acceptance

Roxana Damiescu et al. Trends Pharmacol Sci. 2022 Dec.

Abstract

COVID-19 has put vaccine efficacy under a spotlight. However, the reluctance of people to be vaccinated has postponed the end of the COVID-19 pandemic. Currently, opioid vaccines are being developed, which could help prevent opioid addiction, overdoses, or relapse in combination with medication-assisted therapy. The fear is that the uptake of opioid vaccines could be met by the same reluctance as seen with COVID-19 vaccines.

Trial registration: ClinicalTrials.gov NCT04458545.

Keywords: COVID-19 vaccination; opioid misuse; opioid vaccination; public health; vaccine reluctance.

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Conflict of interest statement

Declaration of interests The authors declare no conflict of interest.

Figures

Figure I
Figure I
Provisional drug overdose death counts. Source: National Center for Health Statistics.
See this image and copyright information in PMC

References

    1. Henry B.F., et al. COVID-19, mental health, and opioid use disorder: old and new public health crises intertwine. Psychol. Trauma Theory Res. Pract. Policy. 2020;12:S111–S112. - PMC - PubMed
    1. Karamchandani K., et al. Critical care pain management in patients affected by the opioid epidemic: a review. Ann. Am. Thorac. Soc. 2018;15:1016–1023. - PubMed
    1. Pravetoni M., Comer S.D. Development of vaccines to treat opioid use disorders and reduce incidence of overdose. Neuropharmacology. 2019;158 - PMC - PubMed
    1. Wang Q.Q., et al. COVID-19 risk and outcomes in patients with substance use disorders: analyses from electronic health records in the United States. Mol. Psychiatry. 2021;26:30–39. - PMC - PubMed
    1. Mellis A.M., et al. Trust in a COVID-19 vaccine among people with substance use disorders. Drug Alcohol Depend. 2021;220 - PMC - PubMed

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