Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Sep 13:15:7249-7264.
doi: 10.2147/IJGM.S376759. eCollection 2022.

Acupuncture for Post-Stroke Cognitive Impairment: An Overview of Systematic Reviews

Affiliations
Review

Acupuncture for Post-Stroke Cognitive Impairment: An Overview of Systematic Reviews

Liuying Li et al. Int J Gen Med. .

Abstract

Background: Post-stroke cognitive impairment (PSCI) is one of the most common complications after stroke. In recent years, as a complementary alternative therapy, many systematic reviews (SRs) and meta-analysis (MAs) have reported the efficacy and safety of acupuncture in improving cognitive function in patients with PSCI, but the quality of evidence is unknown and therefore needs to be evaluated comprehensively.

Aim: We aimed to evaluate the SRs of acupuncture for patients with PSCI, to summarize the evidence quality of SRs to provide scientific evidence.

Methods: We searched for relevant SRs and MAs in seven databases up to March 22, 2022. Two reviewers independently completed literature retrieval, screening, and data extraction. We used A Measurement Tool to Assess Systematic Reviews 2 (AMSTAR 2) to evaluate the methodological quality; the Grading of Recommendations Assessment, Development and Evaluation (GRADE) tool to determine the strength of evidence; and the ROBIS tool to assess RoB.

Results: We identified 14 SRs. The methodological quality of all SRs was low (2/14) or very low (12/14). GRADE results showed 13 were moderate quality (26%), 5 were low quality (10%), and 32 were very-low quality (64%). RoB showed that one SR had a low risk and 13 had a high risk. Moderate quality results showed that combined acupuncture therapy was superior to western medicine or cognitive rehabilitation training in improving cognitive function, the total response rate, and the daily living ability of patients with PSCI.

Conclusion: Based on the evidence, acupuncture appears to be effective and safe in improving cognitive function for patients with PSCI, but the overall quality of SRs is not high. High-quality randomized controlled trials are needed to confirm the effectiveness and safety of acupuncture on the cognitive function of patients with PSCI.

Systematic review registration: PROSPERO CRD42022315441.

Keywords: AMSTAR-2; GRADE; PSCI; acupuncture; overview.

PubMed Disclaimer

Conflict of interest statement

None of the authors stated any conflicts of interest in this study, and there were no potential commercial or financial relationships.

Figures

Figure 1
Figure 1
The detailed flow chart.
Figure 2
Figure 2
The detailed results of RoB.

Similar articles

Cited by

References

    1. Vos T, Lim SS, Abbafati C, et al. Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2020;396(10258):1204–1222. doi:10.1016/S0140-6736(20)30925-9 - DOI - PMC - PubMed
    1. Skrobot OA, Black SE, Chen C, et al. Progress toward standardized diagnosis of vascular cognitive impairment: guidelines from the vascular impairment of cognition classification consensus study. Alzheimers Dement. 2018;14(3):280–292. doi:10.1016/j.jalz.2017.09.007 - DOI - PubMed
    1. Mijajlović MD, Pavlović A, Brainin M, et al. Post-stroke dementia - a comprehensive review. BMC Med. 2017;15(1):11. doi:10.1186/s12916-017-0779-7 - DOI - PMC - PubMed
    1. Yu KH, Cho SJ, Oh MS, et al. Cognitive impairment evaluated with vascular cognitive impairment harmonization standards in a multicenter prospective stroke cohort in Korea. Stroke. 2013;44(3):786–788. doi:10.1161/STROKEAHA.112.668343 - DOI - PubMed
    1. Pollock A, St George B, Fenton M, et al. Top ten research priorities relating to life after stroke. Lancet Neurol. 2012;11(3):209. doi:10.1016/S1474-4422(12)70029-7 - DOI - PubMed