Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Sep 20;12(9):e063611.
doi: 10.1136/bmjopen-2022-063611.

Disparities and implicit bias in the management of low-risk febrile infants: a mixed methods study protocol

Affiliations

Disparities and implicit bias in the management of low-risk febrile infants: a mixed methods study protocol

Colleen K Gutman et al. BMJ Open. .

Abstract

Introduction: The management of low-risk febrile infants presents a model population for exploring how implicit racial bias promotes inequitable emergency care for children who belong to racial, ethnic and language minority groups. Although widely used clinical standards guide the clinical care of febrile infants, there remains substantial variability in management strategies. Deviations from recommended care may be informed by the physician's assessment of the family's values, risk tolerance and access to supportive resources. However, in the fast-paced emergency setting, such assessments may be influenced by implicit racial bias. Despite significant research to inform the clinical care of febrile infants, there is a dearth of knowledge regarding health disparities and clinical guideline implementation. The proposed mixed methods approach will (1) quantify the extent of disparities by race, ethnicity and language proficiency and (2) explore the role of implicit bias in physician-patient communication when caring for this population.

Methods and analysis: With 42 participating sites from the Pediatric Emergency Medicine Collaborative Research Committee, we will conduct a multicenter, cross-sectional study of low-risk febrile infants treated in the emergency department (ED) and apply multivariable logistic regression to assess the association between (1) race and ethnicity and (2) limited English proficiency with the primary outcome, discharge to home without lumbar puncture or antibiotics. We will concurrently perform an interpretive study using purposive sampling to conduct individual semistructured interviews with (1) minority parents of febrile infants and (2) paediatric ED physicians. We will triangulate or compare perspectives to better elucidate disparities and bias in communication and medical decision-making.

Ethics and dissemination: This study has been approved by the University of Florida Institutional Review Board. All participating sites in the multicenter analysis will obtain local institutional review board approval. The results of this study will be presented at academic conferences and in peer-reviewed publications.

Keywords: accident & emergency medicine; paediatric A&E and ambulatory care; paediatrics.

PubMed Disclaimer

Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Mixed methods study design. EDs, emergency departments; PEMCRC, Pediatric Emergency Medicine Collaborative Research Committee.
Figure 2
Figure 2
Cohort identification strategy for the multicenter cross-sectional analysis of disparities in the management of low-risk febrile infants. ED, emergency department.
Figure 3
Figure 3
Pediatric Emergency Medicine Collaborative Research Committee network member sites with intent to participate in the cross-sectional cohort analysis of disparities by race, ethnicity and language proficiency in the management of low-risk febrile infants. Participation requires completion of all local and study-wide regulatory requirements.

References

    1. Kuppermann N, Dayan PS, Levine DA, et al. . A clinical prediction rule to identify febrile infants 60 days and younger at low risk for serious bacterial infections. JAMA Pediatr 2019;173:342–51. 10.1001/jamapediatrics.2018.5501 - DOI - PMC - PubMed
    1. Mintegi S, Bressan S, Gomez B, et al. . Accuracy of a sequential approach to identify young febrile infants at low risk for invasive bacterial infection. Emerg Med J 2014;31:e19–24. 10.1136/emermed-2013-202449 - DOI - PubMed
    1. Aronson PL, Shabanova V, Shapiro ED, et al. . A prediction model to identify febrile infants ≤60 days at low risk of invasive bacterial infection. Pediatrics 2019;144. 10.1542/peds.2018-3604 - DOI - PMC - PubMed
    1. Pantell RH, Roberts KB, Adams WG, et al. . Evaluation and management of well-appearing febrile infants 8 to 60 days old. Pediatrics 2021;148:e2021052228. 10.1542/peds.2021-052228 - DOI - PubMed
    1. Biondi EA, McCulloh R, Staggs VS, et al. . Reducing variability in the infant sepsis evaluation (revise): a national quality initiative. Pediatrics 2019;144:2201. 10.1542/peds.2018-2201 - DOI - PubMed

Publication types

Substances

LinkOut - more resources