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Case Reports
. 2022 Jun 30;33(2):252-255.
doi: 10.31138/mjr.33.2.252. eCollection 2022 Jun.

Familial Mediterranean Fever Mimicking Whipple's Disease: A Case Report and Review of the Literature

Sofia Flouda  1   2 , Georgia-Savvina Moysidou  1 , Christina Damoulari  1 , Noemin Kapsala  1   2 , Maria Kosmetatou  1 , Anastasia Antoniadou  1 , Dimitros Boumpas  1   2 , Pelagia Katsimpri  1
Affiliations
Case Reports

Familial Mediterranean Fever Mimicking Whipple's Disease: A Case Report and Review of the Literature

Sofia Flouda et al. Mediterr J Rheumatol. .
No abstract available

Keywords: Whipple’s Disease; familial Mediterranean fever.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1.
Figure 1.
Laboratory evaluation of the reported patient with a diagnosis of FMF (heterozygous of P369S) under treatment with canakinumab and FUO, chronic diarrhoea, and malabsorption. Electrocardiogram revealed no abnormalities.
Figure 2.
Figure 2.
CT scan of the abdomen: paraaortic and mesenteric lymphadenopathy, hyperaemia/congestion of the mesenteric vessels, turbidity of the mesenteric fat, and enteritis.
Figure 3.
Figure 3.
Periodic Acid-Schiff (PAS) staining-Marked accumulation of PAS-positive macrophages (white arrow) on submucosa -Presence of fibrosis (black arrow) suggesting a chronic process- Rod-shaped microorganisms - typically in macrophages- Lamina propria macrophages usually abundant.
See this image and copyright information in PMC

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