Harmonizing Surveillance Methodologies for Group A Streptococcal Diseases
- PMID: 36128412
- PMCID: PMC9474938
- DOI: 10.1093/ofid/ofac210
Harmonizing Surveillance Methodologies for Group A Streptococcal Diseases
Abstract
Group A Streptococcus (Strep A) is responsible for a significant global health and economic burden. The recent prioritization of Strep A vaccine development by the World Health Organization has prompted global research activities and collaborations. To progress this prioritization, establishment of robust surveillance for Strep A to generate updated regional disease burden estimates and to establish platforms for future impact evaluation is essential. Through the activities of the Strep A Vaccine Global Consortium (SAVAC), we have refined and harmonized surveillance protocols for 7 Strep A disease endpoints with a view that these will form part of surveillance standards for ongoing research and public health activities.
Keywords: Streptococcus pyogenes; epidemiology; group A Streptococcus; surveillance.
© The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America.
Conflict of interest statement
Potential conflicts of interest. H. C. M. has received funding from MSD under the Merck Investigator Studies Program, outside the submitted work. All other authors report no potential conflicts of interest. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed.
Similar articles
-
The Streptococcus pyogenes vaccine landscape.NPJ Vaccines. 2023 Feb 14;8(1):16. doi: 10.1038/s41541-023-00609-x. NPJ Vaccines. 2023. PMID: 36788225 Free PMC article. Review.
-
The Australian burden of invasive group A streptococcal disease: a narrative review.Intern Med J. 2021 Jun;51(6):835-844. doi: 10.1111/imj.14885. Intern Med J. 2021. PMID: 32372512 Review.
-
Standardization of Epidemiological Surveillance of Invasive Group A Streptococcal Infections.Open Forum Infect Dis. 2022 Sep 15;9(Suppl 1):S31-S40. doi: 10.1093/ofid/ofac281. eCollection 2022 Sep. Open Forum Infect Dis. 2022. PMID: 36128405 Free PMC article.
-
Safety and immunogenicity of a 30-valent M protein-based group a streptococcal vaccine in healthy adult volunteers: A randomized, controlled phase I study.Vaccine. 2020 Feb 5;38(6):1384-1392. doi: 10.1016/j.vaccine.2019.12.005. Epub 2019 Dec 13. Vaccine. 2020. PMID: 31843270 Clinical Trial.
-
A Strep A vaccine global demand and return on investment forecast to inform industry research and development prioritization.NPJ Vaccines. 2023 Aug 9;8(1):113. doi: 10.1038/s41541-023-00690-2. NPJ Vaccines. 2023. PMID: 37558685 Free PMC article.
Cited by
-
Correlates of immunity to Group A Streptococcus: a pathway to vaccine development.NPJ Vaccines. 2023 Jan 17;8(1):1. doi: 10.1038/s41541-022-00593-8. NPJ Vaccines. 2023. PMID: 36650164 Free PMC article. Review.
-
Polymeric epitope-based vaccine induces protective immunity against group A Streptococcus.NPJ Vaccines. 2023 Jul 14;8(1):102. doi: 10.1038/s41541-023-00695-x. NPJ Vaccines. 2023. PMID: 37452052 Free PMC article.
-
Capturing the complete clinical spectrum and incidence of severe acute Group A Streptococcus (GAS) disease: a population-based study in Auckland, New Zealand.Lancet Reg Health West Pac. 2025 Jun 12;59:101600. doi: 10.1016/j.lanwpc.2025.101600. eCollection 2025 Jun. Lancet Reg Health West Pac. 2025. PMID: 40568344 Free PMC article.
References
-
- Cannon JW, Jack S, Wu Y, et al. . An economic case for a vaccine to prevent group A Streptococcus skin infections. Vaccine 2018; 36:6968–78. - PubMed
-
- Carapetis JR, Steer AC, Mulholland EK, Weber M. The global burden of group A streptococcal diseases. Lancet Infect Dis 2005; 5:685–94. - PubMed
-
- Hand RM, Snelling TL, Carapetis JR.. 40: Group A Streptococcus. In: Ryan ET, Hill DR, Solomon T, et al., eds. Hunter’s Tropical Medicine and Emerging Infectious Diseases, 10th ed. London: Elsevier; 2020:429–38.
-
- White A. WHO resolution on rheumatic heart disease. Eur Heart J 2018; 39:4233. - PubMed
LinkOut - more resources
Full Text Sources