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Review
. 2022 Sep 17;9(9):309.
doi: 10.3390/jcdd9090309.

Pulmonary Vascular Sequelae of Palliated Single Ventricle Circulation: Arteriovenous Malformations and Aortopulmonary Collaterals

Andrew D Spearman  1   2 , Salil Ginde  1   2   3
Affiliations
Review

Pulmonary Vascular Sequelae of Palliated Single Ventricle Circulation: Arteriovenous Malformations and Aortopulmonary Collaterals

Andrew D Spearman et al. J Cardiovasc Dev Dis. .

Abstract

Children and adults with single ventricle congenital heart disease (CHD) develop many sequelae during staged surgical palliation. Universal pulmonary vascular sequelae in this patient population include two inter-related but distinct complications: pulmonary arteriovenous malformations (PAVMs) and aortopulmonary collaterals (APCs). This review highlights what is known and unknown about these vascular sequelae focusing on diagnostic testing, pathophysiology, and areas in need of further research.

Keywords: Fontan; Glenn; aortopulmonary collaterals; congenital heart disease; hepatic factor; pulmonary arteriovenous malformations; single ventricle.

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Conflict of interest statement

The authors declare no conflict of interest.

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