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Comment
. 2022 Sep 21;13(9):687-689.
doi: 10.1016/j.cels.2022.08.005.

Unraveling phenotypic plasticity and evolution in small cell lung cancer

Aritro Nath  1
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Unraveling phenotypic plasticity and evolution in small cell lung cancer

Aritro Nath. Cell Syst. .
Free article

Abstract

Malignant cell populations in a tumor often exist in distinct phenotypic states. Deciphering tumor heterogeneity requires determining how many such unique states exist and what the biological traits associated with each are. Archetype analysis of SCLC transcriptomes reveals key phenotypic states in SCLC tumors and their patterns of evolution.

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Conflict of interest statement

Declaration of interests The author declares no competing interests.

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