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Case Reports
. 2022 Sep 5;11(9):1200.
doi: 10.3390/antibiotics11091200.

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Bordetella bronchiseptica Co-Infection in a Stem Cell Transplant Patient

Michael Pierce  1 , Wendy Slipke  2 , Mark Biagi  2   3
Affiliations
Case Reports

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Bordetella bronchiseptica Co-Infection in a Stem Cell Transplant Patient

Michael Pierce et al. Antibiotics (Basel). .

Abstract

Bordetella bronchiseptica infections may be overlooked by clinicians due to the uncommon encounter of this pathogen in humans and common isolation of co-pathogens. However, the isolation of B. bronchiseptica in immunocompromised individuals may represent a true infection. We report our experience with the fatal case of a stem cell transplant recipient, co-infected with SARS-CoV-2 and B. bronchiseptica, who was considered fully vaccinated (two doses) at the time of her case in spring 2021. Future studies are needed to evaluate the incidence of bacterial co-infections in immunosuppressed individuals with SARS-CoV-2 and clinicians should remain cognizant of the potential pathogenic role of uncommon pathogens isolated in these individuals.

Keywords: Bordetella bronchiseptica; COVID-19; SARS-CoV-2; co-infection.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Chest X-rays showing (A) baseline bilateral infiltrates on day 0 and (B) mild improvement in the patchy airspace opacity in the right lower lobe and stable patchy opacity in the left lower lobe on day 11.
See this image and copyright information in PMC

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