doi: 10.1111/j.1432-1033.1978.tb12607.x.
Dimer state of protein L7/L12 and EF-G-dependent reactions of ribosomes
- PMID: 361401
- DOI: 10.1111/j.1432-1033.1978.tb12607.x
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Dimer state of protein L7/L12 and EF-G-dependent reactions of ribosomes
Eur J Biochem.
1978 Oct.
Free article
Abstract
A number of different monomer and dimer derivatives of protein L7/L12 has been studied in EF-G-dependent reactions on the ribosome. It has been shown that only dimer derivatives of protein L7/L12 are able to interact with the ribosome. This means that it is the dimer forms of protein L7/L12 that are present in the functionally active ribosome. It is likely that the N-terminal sequence of protein L7/L12 is responsible for dimerization of the protein in solution and at the same time contributes mainly to the interaction of the protein L7/L12 dimer with the ribosome. The results obtained suggest that there are four copies of protein L7/L12 in the translating ribosome.
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