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. 2022 Sep 8;10(9):1725.
doi: 10.3390/healthcare10091725.

Effect of Lockdown and Mass Testing for the SARS-CoV-2 Omicron Epidemic on Reducing New Infections in Shenzhen, China

Affiliations

Effect of Lockdown and Mass Testing for the SARS-CoV-2 Omicron Epidemic on Reducing New Infections in Shenzhen, China

Xinxin Han et al. Healthcare (Basel). .

Abstract

On 14 March 2022, China's tech hub Shenzhen, a mega-city with more than 18 million inhabitants, imposed a one-week citywide lockdown immediately after it observed a surge in infections. We assessed the effect of this one-week lockdown, coupled with mass testing, on reducing the daily number of new confirmed cases and asymptomatic cases during the Omicron wave, using an interrupted time series analysis approach. Our analysis suggests that the one-week citywide lockdown in Shenzhen was effective at lowering both daily new confirmed cases and asymptomatic cases during the Omicron wave. Early detection ensures timely isolation and treatment of infected patients in designated hospitals, and therefore helps lower the prevalence of confirmed cases and asymptomatic cases. Our findings of the immediate increase in asymptomatic cases after lockdown warrant further verifications in other city epidemic scenarios.

Keywords: asymptomatic cases; infections; lockdown; omicron epidemic.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Trends in daily new confirmed cases and asymptomatic cases before and after the implementation of lockdown in Shenzhen, China, 16 January to 3 April 2022.
Figure 1
Figure 1
Trends in daily new confirmed cases and asymptomatic cases before and after the implementation of lockdown in Shenzhen, China, 16 January to 3 April 2022.
Figure 2
Figure 2
Trend in daily number of nucleic acid testing during 6 January to 3 April 2022 in Shenzhen, China.

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References

    1. Zhang X., Zhang W., Chen S. Shanghai’s life-saving efforts against the current omicron wave of the COVID-19 pandemic. Lancet. 2022;399:2011–2012. doi: 10.1016/S0140-6736(22)00838-8. - DOI - PMC - PubMed
    1. Talic S., Shah S., Wild H., Gasevic D., Maharaj A., Ademi Z., Li X., Xu W., Mesa-Eguiagaray I., Rostron J., et al. Effectiveness of public health measures in reducing the incidence of COVID-19, SARS-CoV-2 transmission, and COVID-19 mortality: Systematic review and meta-analysis. BMJ. 2021;375:e068302. doi: 10.1136/bmj-2021-068302. - DOI - PMC - PubMed
    1. Suzuki R., Yamasoba D., Kimura I., Wang L., Kishimoto M., Ito J., Morioka Y., Nao N., Nasser H., Uriu K., et al. Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant. Nature. 2022;603:700–705. doi: 10.1038/s41586-022-04462-1. - DOI - PMC - PubMed
    1. Lauer S.A., Grantz K.H., Bi Q., Jones F.K., Zheng Q., Meredith H.R., Azman A.S., Reich N.G., Lessler J. The incubation period of coronavirus disease 2019 (COVID-19) from publicly reported confirmed cases: Estimation and application. Ann. Intern. Med. 2020;172:577–582. doi: 10.7326/M20-0504. - DOI - PMC - PubMed
    1. Li Q., Guan X., Wu P., Wang X., Zhou L., Tong Y., Ren R., Leung K.S., Lau E.H., Wong J.Y., et al. Early transmission dynamics in Wuhan, China, of novel coronavirus–infected pneumonia. N. Engl. J. Med. 2020;382:1199–1207. doi: 10.1056/NEJMoa2001316. - DOI - PMC - PubMed

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