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. 2022 Aug 26;12(9):1387.
doi: 10.3390/jpm12091387.

Communications Is Time for Care: An Italian Monocentric Survey on Human Papillomavirus (HPV) Risk Information as Part of Cervical Cancer Screening

Miriam Dellino  1   2 , Eliano Cascardi  3   4 , Valentina Tomasone  1 , Rosanna Zaccaro  2 , Katia Maggipinto  2 , Maria Elena Giacomino  1 , Miriana De Nicolò  1 , Simona De Summa  5 , Gerardo Cazzato  6 , Salvatore Scacco  7 , Antonio Malvasi  1 , Vincenzo Pinto  1 , Ettore Cicinelli  1 , Carmine Carriero  1 , Giovanni Di Vagno  2 , Gennaro Cormio  8 , Chiara Antonia Genco  9
Affiliations

Communications Is Time for Care: An Italian Monocentric Survey on Human Papillomavirus (HPV) Risk Information as Part of Cervical Cancer Screening

Miriam Dellino et al. J Pers Med. .

Abstract

Human papilloma virus (HPV) infection could be considered a social disease, both for its high incidence, especially in younger subjects, and for the risk of neoplastic evolution linked to viral infection. Therefore, the National Health System, in collaboration with the state, must help women to understand the oncological risk of HPV and suitable methods of prevention. We conducted an Italian monocentric survey on HPV risk information as part of cervical cancer screening. An anonymous questionnaire was administered to 200 women with high-risk positive HPV and low-grade cervical lesions during second-level cervical cancer screening at the Gynecology and Obstetrics Unit of the "San Paolo" Hospital. From this survey, the need to improve communication for patients has emerged, as currently it is not exhaustive. In response to this need, organizational changes have been implemented to centralize the moment of counseling in the second levels of screening and to improve the training of health workers in level I as well as family doctors. In addition, psychological support was also proposed to patients who requested it, as was the dissemination of material such as that produced by GISCI (Italian Cervico-Carcinoma Screening Group) and updated in May 2018, which provides 100 answers to questions on HPV in order to achieve effective and comprehensive communication. This investigation requires further development, and the expansion of this investigation to the multicenter level is already underway. Therefore, this survey will represent a cornerstone for further discussion on the topic considering the necessity of appropriate communication in the oncological context.

Keywords: CIN; HPV; cervical cancer; cervical lesion; health promotion; precision medicine; screening.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Correlation plot depicting Pearson residual related to response to question 4. Univariate logistic regression was performed to identify which of the parameters, evaluated by the questionnaire, are able to influence appropriate communication on Human Papillomavirus risks.
Figure 2
Figure 2
Forest plot related to multivariate logistic regression.
Figure 3
Figure 3
Example image of the etiopathogenesis of HPV to optimize counseling with the patient (HR: high risk; LR: low risk).
Figure 4
Figure 4
Example image of the tools currently available to counteract the pathogenesis of HPV-related infection (ASC-US: atypical squamous cells of undetermined significance, ASC-H: atypical squamous cells cannot exclude H-SIL, L-SIL: low-grade squamous intraepithelial lesions, H-SIL: high-grade squamous intraepithelial lesions, CR: cervical carcinoma).
See this image and copyright information in PMC

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References

    1. WHO Human Papillomavirus (HPV) and Cervical Cancer. 2020. [(accessed on 22 February 2022)]. Available online: https://www.who.int/en/news-room/fact-sheets/detail/human-papillomavirus....
    1. Bansal A., Singh M.P., Rai B. Human papillomavirus-associated cancers: A growing global problem. Int. J. Appl. Basic Med. Res. 2016;6:84–89. doi: 10.4103/2229-516X.179027. - DOI - PMC - PubMed
    1. Tamma R., Limongelli L., Maiorano E., Pastore D., Cascardi E., Tempesta A., Carluccio P., Mastropasqua M.G., Capodiferro S., Covelli C., et al. Vascular density and inflammatory infiltrate in primary oral squamous cell carcinoma and after allogeneic hematopoietic stem cell transplantation. Ann. Hematol. 2019;98:979–986. doi: 10.1007/s00277-018-3575-3. - DOI - PubMed
    1. Limongelli L., Cascardi E., Capodiferro S., Favia G., Corsalini M., Tempesta A., Maiorano E. Multifocal Amelanotic Melanoma of the Hard Palate: A Challenging Case. Diagnostics. 2020;10:424. doi: 10.3390/diagnostics10060424. - DOI - PMC - PubMed
    1. Verginelli F., Pisacane A., Gambardella G., D’Ambrosio A., Candiello E., Ferrio M., Panero M., Casorzo L., Benvenuti S., Cascardi E., et al. Cancer of unknown primary stem-like cells model multi-organ metastasis and unveil liability to MEK inhibition. Nat. Commun. 2021;12:2498. doi: 10.1038/s41467-021-22643-w. - DOI - PMC - PubMed

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