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Review
. 2022 Sep 6;27(18):5765.
doi: 10.3390/molecules27185765.

A Comprehensive Review with Updated Future Perspectives on the Ethnomedicinal and Pharmacological Aspects of Moringa oleifera

Ummi Kalthum Azlan  1 , Ahmed Mediani  1 , Emelda Rosseleena Rohani  1 , Xiaohui Tong  2 , Rongchun Han  3 , Norazlan Mohmad Misnan  4 , Faidruz Azura Jam  5 , Hamidun Bunawan  1 , Murni Nazira Sarian  1 , Hamizah Shahirah Hamezah  1
Affiliations
Review

A Comprehensive Review with Updated Future Perspectives on the Ethnomedicinal and Pharmacological Aspects of Moringa oleifera

Ummi Kalthum Azlan et al. Molecules. .

Abstract

Moringa oleifera is an ancient remedy plant, known as the miraculous plant due to its many prominent uses and significant health benefits. It is a nutrient-rich plant, with exceptional bioactive compounds, such as polyphenols that possess several medicinal properties. Many significant studies have been carried out to evaluate the ethnomedicinal and pharmacological properties of M. oleifera in various applications. Therefore, this comprehensive review compiles and summarizes important findings from recent studies on the potential properties of different parts of M. oleifera. The pharmacological properties of M. oleifera have been studied for various potential biological properties, such as cardio-protective, anti-oxidative, antiviral, antibacterial, anti-diabetic and anti-carcinogenic effects. Therefore, the potential of this plant is even more anticipated. This review also highlights the safety and toxicity effects of M. oleifera treatment at various doses, including in vitro, in vivo and clinical trials from human studies.

Keywords: M. oleifera; antioxidant activity; bioactive compounds; nutritional composition; pharmacological properties; polyphenols.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
The uses of M. oleifera in various applications.
Figure 2
Figure 2
World map distributions of M. oleifera. World map image was obtained and modified from Outline World Map (free access).
Figure 3
Figure 3
The different parts of M. oleifera: (A) leaves, (B) stem and bark, (C) pods, (D) flowers and sepals and (E) seeds.
Figure 4
Figure 4
Bioactive compounds present in different parts of M. oleifera.
Figure 5
Figure 5
The reported biological properties of M. oleifera.
See this image and copyright information in PMC

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