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. 2022 Sep;78(Suppl 1):S186-S193.
doi: 10.1016/j.mjafi.2020.12.019. Epub 2021 Mar 26.

An observational study on ocular manifestations in patients of psoriasis in a tertiary care hospital in western India

Ankita Singh  1 , Poninder Kumar  2 , Preema Sinha  3 , Jaya Kaushik  4 , D Srujana  5 , Rakesh Shetty  1 , Divya Kochhar  1 , Durga Madhab Tripathy  6
Affiliations

An observational study on ocular manifestations in patients of psoriasis in a tertiary care hospital in western India

Ankita Singh et al. Med J Armed Forces India. 2022 Sep.

Abstract

Background: The aim of the study is to observe the ocular manifestation in patients of psoriasis.

Methods: All the diagnosed cases of Psoriasis by the dermatology department of this tertiary care hospital were included in this study. Relevant details of the history pertaining to disease duration, type of psoriasis, and treatment undertaken including ocular symptoms were obtained. Disease severity was quantified using the PASI score. Complete ocular examination including intraocular pressure, Schirmer I and II tests, Tear Film Breakup Tme (TBUT); was carried out for all the patients.

Results: Of 126 patients of psoriasis, ocular manifestations were seen in 76 patients (60.3%). Dry eyes (27%) and blepharitis (15.9%) were the most common ocular manifestations. Uveitis was seen in 3.2% of the patients of which 75% patients were HA B27-positive psoriatic arthritis, which was statistically significant (p = 0.001). There was no statistical correlation between duration of the disease and ocular manifestations (p value is 0.077 using chi square test). The ocular manifestations were more common in patients with PASI score 10 when compared with the patients with PASI score 10 (p value = 0.028) which was statistically significant.

Conclusions: In our study, prevalence of ocular manifestation was 60.3% which increased with the increasing PASI score. Dry eyes and blepharitis were the most common manifestations. Hence, routine ocular examination is recommended in patients with psoriasis.

Keywords: Blepharitis; Dry eyes; Ocular manifestations; PASI score; Psoriasis.

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Conflict of interest statement

The authors have none to declare.

Figures

Graph 1
Graph 1
Graph showing number of patients with ocular manifestations in different age groups.
Fig. 1
Fig. 1
Few of the clinical photographs of the different patterns of psoriasis seen in our study population. a) and b) Erythrodermic psoriasis; c) plaque psoriasis; d) pustular psoriasis.
Graph 2
Graph 2
Graph showing the number of patients with ocular manifestations depending on the severity of the disease.
Fig. 2
Fig. 2
Ocular manifestations as observed in the study population; a) pterygium; b) conjunctivitis; c) blepharitis; d) episcleritis; e) cataract; f) chronic uveitis with festooned pupil; g) fundus photograph of macular edema; h) macular edema on FFA; i) cystoid macular edema on Optical Coherence Tomography.
Graph 3
Graph 3
: Graphical representation of ocular manifestations.
Graph 4
Graph 4
: Graphical distribution of tear film abnormalities in the study population based on the test results.
See this image and copyright information in PMC

References

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