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Case Reports
. 2022 Aug 19;14(8):e28163.
doi: 10.7759/cureus.28163. eCollection 2022 Aug.

Multifocal Neuroarthropathy of the Knee and Foot Induced by Physical Training of the Lower Extremities in a Patient With Latent Autoimmune Diabetes in Adults

Affiliations
Case Reports

Multifocal Neuroarthropathy of the Knee and Foot Induced by Physical Training of the Lower Extremities in a Patient With Latent Autoimmune Diabetes in Adults

Chika Kojima et al. Cureus. .

Abstract

Charcot neuroarthropathy is a progressive arthropathy associated with neuropathy. In patients with diabetes, Charcot neuroarthropathy mostly affects the foot. In the present case, we encountered a rare presentation of Charcot neuroarthropathy of the knee and foot in a patient with latent autoimmune diabetes in adults. The patient, who may have developed the disease as a result of inappropriate physical exercise, was treated with total knee arthroplasty.

Keywords: charcot knee; diabetic polyneuropathy; latent autoimmune diabetes; neuroarthropathy; physical training; total knee arthroplasty.

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Conflict of interest statement

The authors have declared financial relationships, which are detailed in the next section.

Figures

Figure 1
Figure 1. The lateral views of the foot and ankle.
A: Fragmentation of the calcaneal bone with associated bony erosions and disorganization in the right foot. B: Normal shape and alignment of the left foot.
Figure 2
Figure 2. Radiographs of the left knee on admission.
Lateral (left) and anteroposterior (right) views show a comminuted fracture of the medial tibial condyle.
Figure 3
Figure 3. Postoperative radiographs of the left knee.
Lateral (left) and anteroposterior (right) views show the restored alignment of the left knee after total knee arthroplasty.

References

    1. Current concepts underlying the pathophysiology of acute Charcot neuroarthropathy in the diabetic foot and ankle. Yates TH, Cooperman SR, Shofler D, Agrawal DK. Expert Rev Clin Immunol. 2020;16:839–845. - PubMed
    1. Spectrum of diabetic neuropathies. Sasaki H, Kawamura N, Dyck PJ, Dyck PJ, Kihara M, Low PA. Diabetol Int. 2020;11:87–96. - PMC - PubMed
    1. Current clinical state of type 1 diabetes in Saitama prefecture. Oikawa Y, Hashimoto K, Hara K, et al. Diabetol Int. 2022;13:436–446. - PMC - PubMed
    1. Quantitative vibration perception threshold in assessing diabetic polyneuropathy: should the cut-off value be adjusted for Chinese individuals with type 2 diabetes? Liu M, Gao Y, Chen DW, Lin S, Wang C, Chen LH, Ran XW. J Diabetes Investig. 2021;12:1663–1670. - PMC - PubMed
    1. Current concepts in the management of diabetic polyneuropathy. Ziegler D, Papanas N, Schnell O, Nguyen BD, Nguyen KT, Kulkantrakorn K, Deerochanawong C. J Diabetes Investig. 2021;12:464–475. - PMC - PubMed

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