Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Nov;28(11):2290-2293.
doi: 10.3201/eid2811.220364. Epub 2022 Sep 23.

Rift Valley Fever Outbreak during COVID-19 Surge, Uganda, 2021

Rift Valley Fever Outbreak during COVID-19 Surge, Uganda, 2021

Caitlin M Cossaboom et al. Emerg Infect Dis. 2022 Nov.

Abstract

Rift Valley fever, endemic or emerging throughout most of Africa, causes considerable risk to human and animal health. We report 7 confirmed Rift Valley fever cases, 1 fatal, in Kiruhura District, Uganda, during 2021. Our findings highlight the importance of continued viral hemorrhagic fever surveillance, despite challenges associated with the COVID-19 pandemic.

Keywords: Bunyavirales; Rift Valley fever; Uganda; outbreak investigation; vector-borne infections; viral hemorrhagic fever; zoonoses; zoonotic.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Locations where the index case-patient of a Rift Valley fever outbreak in Kinoni Subcounty sought care during the period of acute illness preceding her death, Uganda, 2021. Arrows indicate route patient followed during attempts to find diagnosis and care. Inset shows location of Uganda in Africa.
Figure 2
Figure 2
Phylogenetic analysis of Kenya-2 clade Rift Valley fever virus small segment from an outbreak in Uganda, 2021, compared with available full-length segments from GenBank (accession numbers shown). Green shading indicates sequence from Uganda outbreak; blue shading indicates historic RVFV sequences from Uganda. Red numbers indicate nodes with bootstrap support >70%. Complete phylogenies of small and large segments are shown in the Appendix.

References

    1. Bird BH, Ksiazek TG, Nichol ST, Maclachlan NJ. Rift Valley fever virus. J Am Vet Med Assoc. 2009;234:883–93. 10.2460/javma.234.7.883 - DOI - PubMed
    1. Elliott RS. Bunyaviridae. In: Knipe DN, Howley PM, editors. Fields virology, 6th ed. Philadelphia: Lippincott Williams and Wilkins; 2013. p. 1245–78.
    1. Nyakarahuka L, de St Maurice A, Purpura L, Ervin E, Balinandi S, Tumusiime A, et al. Prevalence and risk factors of Rift Valley fever in humans and animals from Kabale district in Southwestern Uganda, 2016. PLoS Negl Trop Dis. 2018;12:e0006412. 10.1371/journal.pntd.0006412 - DOI - PMC - PubMed
    1. Al-Hamdan NA, Panackal AA, Al Bassam TH, Alrabea A, Al Hazmi M, Al Mazroa Y, et al. The risk of nosocomial transmission of Rift Valley fever. PLoS Negl Trop Dis. 2015;9:e0004314. 10.1371/journal.pntd.0004314 - DOI - PMC - PubMed
    1. Madani TA, Al-Mazrou YY, Al-Jeffri MH, Mishkhas AA, Al-Rabeah AM, Turkistani AM, et al. Rift Valley fever epidemic in Saudi Arabia: epidemiological, clinical, and laboratory characteristics. Clin Infect Dis. 2003;37:1084–92. 10.1086/378747 - DOI - PubMed