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. 2023 Jan:107:100-101.
doi: 10.1016/j.ejim.2022.09.014. Epub 2022 Sep 19.

Harm of early dexamethasone for COVID-19 and bias in randomized trials

Isaac Núñez  1 , Yanink Caro-Vega  2 , Adrian Soto-Mota  3
Affiliations

Harm of early dexamethasone for COVID-19 and bias in randomized trials

Isaac Núñez et al. Eur J Intern Med. 2023 Jan.
No abstract available

Keywords: COVID-19; Confounding; Dexamethasone; Randomized trials; Selection bias.

PubMed Disclaimer

Conflict of interest statement

Declaration of Competing Interest None.

Figures

Fig. 1
Fig. 1
A) Causal diagram when stratifying the analysis by ‘Time with symptoms’. B) Causal diagram when stratifying the analysis by ‘Disease severity (hypoxemia)’. Biasing paths are shown in red.
See this image and copyright information in PMC

Dataset described in

  • Tutorial on directed acyclic graphs.
    Digitale JC, Martin JN, Glymour MM. Digitale JC, et al. J Clin Epidemiol. 2022 Feb;142:264-267. doi: 10.1016/j.jclinepi.2021.08.001. Epub 2021 Aug 8. J Clin Epidemiol. 2022. PMID: 34371103 Free PMC article.

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