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. 2023 Nov;29(8):3481-3492.
doi: 10.1111/odi.14391. Epub 2022 Oct 5.

Gender differences in lateral pterygoid muscle in patients with anterior disk displacement

Shuo Wang  1 , Yu Chen  1 , Wei Guo  1 , Dejun She  1 , Yunyang Liao  2 , Zhen Xing  1 , Nan Huang  1 , Hongjie Huang  1 , Dairong Cao  1
Affiliations

Gender differences in lateral pterygoid muscle in patients with anterior disk displacement

Shuo Wang et al. Oral Dis. 2023 Nov.

Abstract

Objective: To use quantitative MRI to assess gender differences in lateral pterygoid muscle (LPM) characteristics in patients with anterior disk displacement (ADD).

Methods: Lateral pterygoid muscle of 51 patients diagnosed with temporomandibular joint disorders (TMD) who underwent T1-weighted Dixon and T1-mapping sequences were retrospectively analyzed. There were 34 female patients (10 with bilateral normal position disk [NP]; 24 with bilateral ADD) and 17 male patients (eight with bilateral NP; nine with bilateral ADD) among them. After controlling for age, differences in fat fraction, T1 value, volume and histogram features related to gender and disk status were tested with 2-way ANCOVA or Quade ANCOVA with Bonferroni correction.

Results: Volume of LPM in NP was significantly smaller than that of ADD (p < 0.001). Fat fraction of LPM in females with NP was significantly higher than males with NP (p < 0.05). Females with ADD showed a significantly higher T1 value (p < 0.05), and higher intramuscular heterogeneity than males with ADD.

Conclusions: Lateral pterygoid muscle in female TMD patients presented more fatty infiltration in the NP stage and might present more fibrosis in the ADD stage compared with males. Together, this leads to more serious intramuscular heterogeneity during the pathogenesis of ADD in females.

Keywords: fatty infiltration; fibrosis; histogram analysis; lateral pterygoid muscle; temporomandibular joint anterior disk displacement.

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REFERENCES

    1. Agha, O., Diaz, A., Davies, M., Kim, H. T., Liu, X., & Feeley, B. T. (2021). Rotator cuff tear degeneration and the role of fibro-adipogenic progenitors. Annals of the New York Academy of Sciences, 1490, 13-28. https://doi.org/10.1111/nyas.14437
    1. Ahn, J. H., Yu, J. S., Park, K. S., Kang, S. H., Huh, J. H., Chang, J. S., Lee, J. H., Kim, M. Y., Nickel, M. D., Kannengiesser, S., Kim, J. Y., & Koh, S. B. (2021). Effect of hepatic steatosis on native T1 mapping of 3T magnetic resonance imaging in the assessment of T1 values for patients with non-alcoholic fatty liver disease. Magnetic Resonance Imaging, 80, 1-8. https://doi.org/10.1016/j.mri.2021.03.015
    1. Bergen, R. V., Ryner, L., & Essig, M. (2020). Comparison of DCE-MRI parametric mapping using MP2RAGE and variable flip angle T1 mapping. Magnetic Resonance Imaging, 19, 725-730. https://doi.org/10.1016/j.mri.2020.01.001
    1. Berry, D. B., Regner, B., Galinsky, V., Ward, S. R., & Frank, L. R. (2018). Relationships between tissue microstructure and the diffusion tensor in simulated skeletal muscle. Magnetic Resonance in Medicine, 80, 317-329. https://doi.org/10.1002/mrm.26993
    1. Bueno, C. H., Pereira, D. D., Pattussi, M. P., Grossi, P. K., & Grossi, M. L. (2018). Gender differences in temporomandibular disorders in adult populational studies: A systematic review and meta-analysis. Journal of Oral Rehabilitation, 45, 720-729. https://doi.org/10.1111/joor.12661

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